Norris F H, Smith R A, Denys E H
Br Med J (Clin Res Ed). 1985 Jul 27;291(6490):259-62. doi: 10.1136/bmj.291.6490.259.
Even in the most severe forms of motor neurone disease--progressive bulbar palsy and amyotrophic lateral sclerosis--the symptoms and disabilities from progressive paralysis may be relieved in many patients by various symptomatic treatments. Quality of life may be improved even in the terminal stage, when narcotic administration should be considered. The physician's proper role is to offer and carefully supervise these treatments, not withhold them. Home care is recommended even for the most severely paralysed, though hospice care may be a good alternative. The underlying principle--to alleviate symptoms--applies to the management of all progressive incurable diseases.
即使在运动神经元病最严重的形式——进行性延髓麻痹和肌萎缩侧索硬化症中,许多患者通过各种对症治疗,其进行性瘫痪所导致的症状和残疾也可能得到缓解。即使在晚期,当应考虑使用麻醉剂时,生活质量也可能得到改善。医生的恰当职责是提供并仔细监督这些治疗,而不是拒绝给予。即使是最严重瘫痪的患者也建议居家护理,不过临终关怀护理可能是个不错的选择。减轻症状这一基本原则适用于所有进行性不治之症的管理。