Mutwaly Raghda F, Elmadina Abdelaziz M, Alrasheed Saif H, Moafa Majid A, Aldakhil Sulaiman
Department of Optometry, College of Applied Medical Sciences, Qassim University, Buraydah, SAU.
Cureus. 2024 Sep 11;16(9):e69168. doi: 10.7759/cureus.69168. eCollection 2024 Sep.
Myopia is associated with changes in the posterior segment of the eye, including the macula, which may contribute to potential blindness. Therefore, the study aims to evaluate the macula integrity in young myopic patients through optical coherence tomography (OCT).
A cross-sectional study was conducted at Qassim University optometry clinics from January to June 2024, involving 30 healthy young males with myopia and 30 with emmetropia. Clinical examination and OCT imaging were used to gather data on macular volume and thickness. The results were analyzed using descriptive statistics and correlation analysis.
The study included 60 myopic eyes and 60 emmetropic eyes. The participants' mean age was 22.10 ± 1.65 years (p = 0.135). A significant difference was found between myopic and emmetropic eyes in fovea, parafovea, perifovea, and total macula thickness and volume (P < 0.05). Additionally, the study showed a significant positive correlation between the magnitude of myopia and fovea thickness (r = 0.297, p = 0.011) and negative correlations with perifovea thickness (r = -0.418, p < 0.001), total macula thickness (r = -0.353, p = 0.003), and total macula volume (r = -0.352, p = 0.003). However, parafoveal thickness had no significant correlation with the severity of myopia (r= -0.107; p=0.207). Fovea thickness was higher in high myopia (255.40 ± 23.51 µm) compared to low (238.69 ± 15.98 µm) and moderate (248.15 ± 8.70 µm) myopia. Perifovea thickness, macula thickness, and macula volume were significantly lower in high myopia (p ˃ 0.05).
Myopia influences macular parameters compared to emmetropia. It increases fovea thickness and decreases total macula thickness and volume as well as perifovea thickness. High myopia has more alterations in macula parameters.
近视与眼球后段的变化有关，包括黄斑区，这可能导致潜在的失明。因此，本研究旨在通过光学相干断层扫描（OCT）评估年轻近视患者的黄斑完整性。
2024年1月至6月在卡西姆大学验光诊所进行了一项横断面研究，纳入30名患有近视的健康年轻男性和30名正视眼者。通过临床检查和OCT成像收集黄斑体积和厚度的数据。使用描述性统计和相关性分析对结果进行分析。
该研究包括60只近视眼和60只正视眼。参与者的平均年龄为22.10±1.65岁（p = 0.135）。近视眼和正视眼在中央凹、旁中央凹、中央凹周围以及黄斑总厚度和体积方面存在显著差异（P < 0.05）。此外，研究显示近视度数与中央凹厚度之间存在显著正相关（r = 0.297，p = 0.011），与中央凹周围厚度（r = -0.418，p < 0.001）、黄斑总厚度（r = -0.353，p = 0.003）和黄斑总体积（r = -0.352，p = 0.003）之间存在负相关。然而，旁中央凹厚度与近视严重程度无显著相关性（r = -0.107；p = 0.207）。高度近视的中央凹厚度（255.40±23.51 µm）高于低度（238.69±15.98 µm）和中度（248.15±8.70 µm）近视。高度近视的中央凹周围厚度、黄斑厚度和黄斑体积显著更低（p ˃ 0.05）。
与正视眼相比，近视会影响黄斑参数。它会增加中央凹厚度，减少黄斑总厚度、体积以及中央凹周围厚度。高度近视的黄斑参数改变更多。
