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从单纯睾丸畸胎瘤到原始神经外胚层肿瘤:一名年轻成人睾丸畸胎瘤恶变伴广泛转移的成功治疗

From pure testicular Teratoma to primitive neuroectodermal tumor: Successful management of Teratoma malignant transformation with widespread metastases in a young adult.

作者信息

Masoumi Navid, Amani-Beni Ali, Ataei Elnaz, Gharib Atoosa, Khorram Amir Alinejad

机构信息

Department of Urology, Shahid Modarress Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Clinical Development Center of Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Urol Case Rep. 2024 Aug 22;56:102830. doi: 10.1016/j.eucr.2024.102830. eCollection 2024 Sep.

Abstract

Midline retroperitoneal masses in young males often present a diagnostic challenge, with metastases from testicular origins being a primary consideration. Beyond the initial pathology of testicular cancer, these masses can undergo transformation, including the development of teratomas. This report describes an unusual case of a calcified retroperitoneal mass originating from a testicular pure teratoma that underwent a rare transformation into a Primitive Neuroectodermal Tumor (PNET), comprising approximately 85 % of the tumor volume. The patient's successful treatment involved a comprehensive approach combining surgical resection and chemotherapy.

摘要

年轻男性的腹膜后中线肿块常常带来诊断挑战,睾丸来源的转移瘤是主要考虑因素。除了睾丸癌的初始病理情况外,这些肿块还可能发生转变,包括畸胎瘤的形成。本报告描述了一例罕见病例,一名睾丸纯畸胎瘤起源的钙化腹膜后肿块发生了罕见转变,转变为原始神经外胚层肿瘤(PNET),该肿瘤约占肿块体积的85%。患者的成功治疗采用了手术切除和化疗相结合的综合方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80ad/11388759/7b9b97fa8816/gr1.jpg

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