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用于茶碱检测的碳纳米材料电化学传感器：综述

Carbon nanomaterials as electrochemical sensors for theophylline: a review.

作者信息

Gabrielle Sutanto Laurencia, Sabilla Syarifa, Wardhana Brasstira Yuva, Ramadani Anggi, Sari Anis Puspita, Anjani Qonita Kurnia, Basirun Wan Jeffrey, Amrillah Tahta, Amalina Ilma, Jiwanti Prastika Krisma

机构信息

Nanotechnology Engineering, Faculty of Advanced Technology and Multidiscipline, Universitas Airlangga Surabaya 60115 Indonesia

Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga Surabaya 60115 Indonesia.

出版信息

RSC Adv. 2024 Sep 11;14(39):28927-28942. doi: 10.1039/d4ra03585b. eCollection 2024 Sep 4.

DOI:10.1039/d4ra03585b
PMID:39263434
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11388037/
Abstract

Theophylline (TP) is a methylxanthine derivative, which serves as a valuable compound in treating respiratory disorders and acts as a bronchodilator agent. However, TP has a limited therapeutic range (20-100 μmol L), demanding precise monitoring to prevent potential drug toxicity even with slight level fluctuations during treatment. Thus, to overcome this limitation, electrochemical methods have been extensively used due to their efficacy in achieving sensitivity, selectivity, and accuracy. In the context of electrochemical sensors, nanocarbon-based materials have gained widespread recognition for their extensive applications. Therefore, this review aims to explore the latest advancements in carbon-based electrodes particularly used for the precise determination of TP through electrochemical methods. The results are expected to provide insights into the profound significance of the methods in enhancing the accuracy and sensitivity for the detection of TP.

摘要

茶碱（TP）是一种甲基黄嘌呤衍生物，是治疗呼吸系统疾病的重要化合物，具有支气管扩张作用。然而，TP的治疗范围有限（20 - 100 μmol/L），即使在治疗期间水平有轻微波动，也需要精确监测以防止潜在的药物毒性。因此，为了克服这一限制，电化学方法因其在实现灵敏度、选择性和准确性方面的功效而被广泛使用。在电化学传感器领域，基于纳米碳的材料因其广泛应用而获得了广泛认可。因此，本综述旨在探讨特别用于通过电化学方法精确测定TP的碳基电极的最新进展。预期这些结果将为这些方法在提高TP检测的准确性和灵敏度方面的深远意义提供见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/6d6c9de95331/d4ra03585b-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/b3a466d2bb73/d4ra03585b-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/f1d3fb361eb7/d4ra03585b-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/1d474d0017a3/d4ra03585b-s2.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/c5722fc217f1/d4ra03585b-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/1db62cc34e4b/d4ra03585b-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/6d6c9de95331/d4ra03585b-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/b3a466d2bb73/d4ra03585b-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/f1d3fb361eb7/d4ra03585b-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/1d474d0017a3/d4ra03585b-s2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/29644741f334/d4ra03585b-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/c5722fc217f1/d4ra03585b-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/1db62cc34e4b/d4ra03585b-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f86/11388037/6d6c9de95331/d4ra03585b-f5.jpg

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本文引用的文献

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An Electrochemical Sensor of Theophylline on a Boron-Doped Diamond Electrode Modified with Nickel Nanoparticles.基于镍纳米粒子修饰的掺硼金刚石电极的茶碱电化学传感器。
Sensors (Basel). 2023 Oct 20;23(20):8597. doi: 10.3390/s23208597.
2
Electrochemical Sensing Platform Based on Carbon Dots for the Simultaneous Determination of Theophylline and Caffeine in Tea.基于碳点的电化学传感平台用于同时测定茶中的茶碱和咖啡因。
Sensors (Basel). 2023 Sep 7;23(18):7731. doi: 10.3390/s23187731.
3
Bronchial thermoplasty attenuates bronchodilator responsiveness.
支气管热成形术会减弱支气管扩张剂的反应性。
Respir Med. 2023 Oct;217:107340. doi: 10.1016/j.rmed.2023.107340. Epub 2023 Jul 7.
4
One stone two birds: anti-inflammatory bronchodilators as a potential pharmacological strategy for COVID-19.一石二鸟：抗炎性支气管扩张剂作为治疗新冠肺炎的一种潜在药理学策略
Front Pharmacol. 2023 May 4;14:1185076. doi: 10.3389/fphar.2023.1185076. eCollection 2023.
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By deflating the lungs pulmonologists help the cardiologists. A literature review.通过使肺部萎陷，肺科医生帮助了心脏病专家。一项文献综述。
Pulmonology. 2023 Dec;29 Suppl 4:S86-S91. doi: 10.1016/j.pulmoe.2023.02.011. Epub 2023 Apr 6.
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Multi-omic approach associates blood methylome with bronchodilator drug response in pediatric asthma.多组学方法将血液甲基组与儿童哮喘的支气管扩张剂药物反应相关联。
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7
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