Kuschel Kristian, Seifert Roland
Institute for Pharmacology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Naunyn Schmiedebergs Arch Pharmacol. 2025 Mar;398(3):2739-2751. doi: 10.1007/s00210-024-03401-3. Epub 2024 Sep 12.
The Deutsche Apotheker Zeitung (DAZ, German Pharmacist Journal) is an independent pharmaceutical newspaper focusing on science and practice, mainly for the profession of pharmacist. In this study, drug advertising in the DAZ was analysed. To our knowledge, there is little scientific data available on drug advertising in professional journals. We assumed that professional journals provide particularly good background information on the advertised drugs because they are targeted to specialists. All non-prescription medicines and preparations that fall under the Medicines Advertising Law (Heilmittelwerbegesetz, HWG) were studied. The Medicines Advertising Law regulates the legal procedure for advertising medicinal products in Germany. The 167 product advertisements from the 52 issues of 2021 were analysed and checked for compliance with the Medicines Advertising Law. We identified significant deficiencies in compliance with the legislation. These included the lack of mandatory information required by the Medicines Advertising Law, for example the indication of adverse drug reactions and the listing of contraindications. There are very few peer-reviewed references on the efficacy of the advertised preparations. A scientific validation was carried out using the PubMed database, with the result that scientific information was available only for 1/3 of the advertisements. In addition, the appearance and target groups as well as social structures, images and feelings conveyed by the advertising were analysed. This study provides insights into the mechanisms of drug advertising in professional journals, which have not yet been researched to any great extent. Even in professional journals, pharmacological evidence plays a much smaller role than marketing, psychology and traditional social values. It seems that drug manufacturers deliberately ignore the German Medicines Advertising Law to advertise their products in the best possible way. Stricter legal controls should be put in place to prevent this practice and protect consumers from misinformation. This will increase drug safety.
《德国药剂师报》(DAZ,German Pharmacist Journal)是一份独立的药学报纸,专注于科学与实践,主要面向药剂师职业群体。在本研究中,对《德国药剂师报》上的药品广告进行了分析。据我们所知,关于专业期刊上药品广告的科学数据很少。我们认为专业期刊能为所宣传的药品提供特别好的背景信息,因为其受众是专业人士。对所有属于《药品广告法》(Heilmittelwerbegesetz,HWG)范畴的非处方药和制剂进行了研究。《药品广告法》规范了德国药品广告的法律程序。对2021年52期报纸中的167则产品广告进行了分析,并检查其是否符合《药品广告法》。我们发现其在法规遵循方面存在重大缺陷。这些缺陷包括缺乏《药品广告法》要求的强制性信息,例如药品不良反应的说明和禁忌证的列举。关于所宣传制剂疗效的同行评审参考文献非常少。利用PubMed数据库进行了科学验证,结果是仅有三分之一的广告有科学信息。此外,还分析了广告的呈现形式、目标群体以及所传达的社会结构、形象和情感。本研究深入探讨了专业期刊上药品广告的机制,而这方面此前尚未得到充分研究。即使在专业期刊中,药理学证据在其中所起的作用也远小于营销、心理学和传统社会价值观。看来药品制造商故意无视德国《药品广告法》,以便尽可能有效地宣传其产品。应实施更严格的法律管控以防止这种行为,并保护消费者免受错误信息的影响。这将提高用药安全性。