记住少突胶质细胞：揭示它们在阿尔茨海默病中被忽视的作用。
Remember oligodendrocytes: Uncovering their overlooked role in Alzheimer's disease.
机构信息
Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany.
German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
出版信息
PLoS Biol. 2024 Sep 12;22(9):e3002798. doi: 10.1371/journal.pbio.3002798. eCollection 2024 Sep.
PMID:39264958
Abstract
Our understanding of Alzheimer's disease (AD) has evolved from focusing solely on neurons to recognizing the role of glia. A recent study in PLOS Biology revealed that oligodendrocytes are an important source of Aβ that impairs neuronal function.
摘要
我们对阿尔茨海默病（AD）的理解已经从单纯关注神经元发展到认识到神经胶质的作用。最近发表在《PLOS Biology》上的一项研究表明，少突胶质细胞是 Aβ的一个重要来源，它会损害神经元功能。
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