由2-氨基-3-甲基咪唑[4,5-f]喹啉诱导的大鼠肝细胞癌中的活化癌基因。
Activated oncogenes in a rat hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline.
作者信息
Ishikawa F, Takaku F, Nagao M, Ochiai M, Hayashi K, Takayama S, Sugimura T
出版信息
Jpn J Cancer Res. 1985 Jun;76(6):425-8.
PMID:3926575
Abstract
The presence of activated oncogenes in several rat hepatocellular carcinomas induced by 2-amino-3-methylimidazo[4,5-f]-quinoline (IQ) was examined by NIH 3T3 cell transfection assay and Southern blot analysis. In one tumor, IQ4, rat H-ras-1 and another oncogene that did not belong to the ras family were found to be activated.
摘要
通过NIH 3T3细胞转染试验和Southern印迹分析，检测了2-氨基-3-甲基咪唑[4,5-f]喹啉（IQ）诱导的几种大鼠肝细胞癌中活化癌基因的存在情况。在一个名为IQ4的肿瘤中，发现大鼠H-ras-1和另一个不属于ras家族的癌基因被激活。
Zotero 插件