自发性和创伤性颈内动脉夹层流行病学中的性别差异。
Sex differences in the epidemiology of spontaneous and traumatic cervical artery dissections.
作者信息
Schipani Elke, Griffin Kim J, Oakley Carlee I, Keser Zafer
机构信息
Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
出版信息
Stroke Vasc Neurol. 2025 Jun 30;10(3):407-410. doi: 10.1136/svn-2024-003282.
BACKGROUND
Recent studies show cervical artery dissection (CeAD) is equally common between sexes, and that the incidence of CeAD has risen at a greater rate in females than males. In this population-based study, we identify sex differences in patients diagnosed with spontaneous and traumatic CeAD.
METHODS
144 patients with spontaneous or traumatic CeAD were studied for sex differences in medical comorbidities, presenting symptoms and outcomes.
RESULTS
Females were more likely to carry a diagnosis of migraine, while males were more likely to have hyperlipidaemia. Females were more likely to present with neck pain, males with stroke. Females were significantly more likely to develop recurrent dissections in the study period.
CONCLUSIONS
These findings underscore the importance of understanding CeAD through the lens of sex differences and may explain the significant rise in the diagnosis of CeAD in females. These findings support the importance of considering sex-specific risk factors and medical comorbidities with sex predilection in the diagnosis and management of CeAD. Furthermore, it emphasises the importance of female patients understanding risk factors and presenting signs that should prompt evaluation for CeAD.
背景
近期研究表明，颈动脉瘤夹层（CeAD）在两性中同样常见，且女性CeAD的发病率上升速度高于男性。在这项基于人群的研究中，我们确定了诊断为自发性和创伤性CeAD患者的性别差异。
方法
对144例自发性或创伤性CeAD患者的医疗合并症、症状表现和治疗结果进行性别差异研究。
结果
女性更易被诊断为偏头痛，而男性更易患高脂血症。女性更易出现颈部疼痛，男性更易出现中风。在研究期间，女性发生复发性夹层的可能性显著更高。
结论
这些发现强调了从性别差异角度理解CeAD的重要性，并可能解释了女性CeAD诊断显著增加的原因。这些发现支持在CeAD的诊断和管理中考虑性别特异性风险因素以及具有性别倾向的医疗合并症的重要性。此外，它强调了女性患者了解风险因素以及应促使对CeAD进行评估的体征的重要性。
Zotero 插件