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对 HDR GYN 患者治疗用的锥形束 CT 成像环进行全面调试。

Comprehensive commissioning of a cone beam CT imaging ring for treatment of HDR GYN patients.

机构信息

Department of Radiation Oncology, Thomas Jefferson University Hospital, Philadelphia, PA.

Department of Radiation Oncology, Thomas Jefferson University Hospital, Philadelphia, PA.

出版信息

Brachytherapy. 2024 Nov-Dec;23(6):687-697. doi: 10.1016/j.brachy.2024.07.008. Epub 2024 Sep 11.

Abstract

PURPOSE

A new mobile cone beam computed tomography (CBCT) imaging ring (IRm, Elekta, v2.10.6, Veenendaal, Netherlands) has recently been proposed for brachytherapy to improve procedure efficiency. We describe the commissioning process and end-to-end tests for GYN HDR brachytherapy employing IRm CBCT imaging.

MATERIALS AND METHODS

Commissioning included imaging isocenter test, 3D image quality, 2D imaging quality, image dose, and tube characteristics. CIRS HDR GYN phantom and Venezia CT/MR gynecological applicator were used to perform end-to-end (E2E) tests and optimize workflow. Venezia applicator and four interstitial needles were inserted into the phantom and IRm CBCT images were acquired. Phantom and applicator were scanned with CT scanner (Siemens SOMATOM go.Open Pro) using department's pelvis imaging protocol. MR imaging was performed using 0.35T MR Linac TRUFI pulse sequence. CBCT images were registered to CT and MR using rigid registration to assess image quality and applicator geometry fidelity.

RESULTS

All physics tests passed within acceptance tolerances. Registration of CBCT images to MR and CT scans was acceptable for applicator placement. Applicator registration of CBCT images to CT demonstrated excellent agreement of most distal source dwell position (<1 mm). Slice thickness was also measured to be 1.25 mm, within 0.5 mm of its nominal value.

CONCLUSION

Based on E2E and commissioning results, IRm is an appropriate tool for brachytherapy treatment planning. This study demonstrated good image quality in GYN phantom and Venezia applicator using the IRm. Distal source dwell position agreement between CBCT and CT was acceptable for clinical use.

摘要

目的

最近提出了一种新的移动锥形束计算机断层扫描(CBCT)成像环(IRm,Elekta,v2.10.6,Veenendaal,荷兰),用于近距离放射治疗,以提高治疗效率。我们描述了使用 IRm CBCT 成像进行妇科 HDR 近距离放射治疗的调试过程和端到端测试。

材料与方法

调试包括成像等中心测试、3D 图像质量、2D 图像质量、图像剂量和管特性。使用 CIRS HDR GYN 体模和威尼斯 CT/MR 妇科施源器进行端到端(E2E)测试和优化工作流程。将威尼斯施源器和四个间质针插入体模中,并获取 IRm CBCT 图像。使用部门骨盆成像协议对体模和施源器进行 CT 扫描仪(西门子 SOMATOM go.Open Pro)扫描。使用 0.35T MR 线性加速器 TRUFI 脉冲序列进行 MR 成像。使用刚性配准将 CBCT 图像配准到 CT 和 MR 上,以评估图像质量和施源器几何保真度。

结果

所有物理测试均在可接受的容差范围内通过。CBCT 图像与 MR 和 CT 扫描的配准可接受,适用于施源器放置。CBCT 图像与 CT 的施源器配准显示出大多数远端源驻留位置的极好一致性(<1 毫米)。切片厚度也被测量为 1.25 毫米,与名义值相差 0.5 毫米。

结论

基于 E2E 和调试结果,IRm 是一种适用于近距离放射治疗计划的工具。本研究在 GYN 体模和威尼斯施源器中使用 IRm 证明了良好的图像质量。CBCT 和 CT 之间的远端源驻留位置一致性可接受,可用于临床应用。

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