School of Government, Nanjing University, Nanjing, China.
Front Public Health. 2024 Aug 29;12:1455718. doi: 10.3389/fpubh.2024.1455718. eCollection 2024.
The factors influencing vaccination decision-making for newly developed vaccines may be similar to and different from those for established vaccines. Understanding these underlying differences and similarities is crucial for designing targeted measures to promote new vaccines against potential novel viruses.
This study aims to compare public vaccination decisions for newly developed and established vaccines and to identify the differences and similarities in the influencing factors.
A discrete choice experiment (DCE) was conducted on 1,509 representatives of the general population in China to collect data on preferences for the coronavirus disease 2019 (COVID-19) and influenza vaccines, representing the newly developed and established vaccines, respectively. The latent class logit model was used to identify latent classes within the sample, allowing for an analysis of the factors distinctly influencing choices for both types of vaccines.
Participants valued similar attributes for both vaccines. However, concerns about sequelae were more significant for the newly developed vaccine, while effectiveness was prioritized for the established vaccine. Class membership analysis revealed these differences and similarities were significantly correlated with age, health, yearly household income, acquaintances' vaccination status, and risk perception.
The study highlights the need for tailored communication strategies and targeted vaccination interventions. For the newly developed vaccines, addressing concerns about side effects is more crucial. For long-standing vaccines, emphasizing their effectiveness can enhance uptake more significantly. Engaging healthcare providers and community influencers is essential for both vaccines to increase public confidence and vaccination rates. Clear communication and community engagement are critical strategies for addressing public concerns and misinformation, particularly during periods of heightened concern.
影响新开发疫苗接种决策的因素可能与已建立疫苗的因素相似和不同。了解这些潜在的差异和相似之处对于设计针对新疫苗的目标措施以应对潜在的新型病毒至关重要。
本研究旨在比较公众对新开发和已建立疫苗的接种决策，并确定影响因素的异同。
在中国，对 1509 名普通民众进行了离散选择实验（DCE），以收集有关对 2019 年冠状病毒病（COVID-19）和流感疫苗的偏好数据，分别代表新开发和已建立的疫苗。使用潜在类别逻辑模型在样本中识别潜在类别，以分析两种类型的疫苗明显影响选择的因素。
参与者对两种疫苗的相似属性给予了相同的重视。然而，对新开发疫苗的后遗症的担忧更为严重，而对已建立疫苗的有效性则更为优先。类别成员分析表明，这些差异和相似之处与年龄、健康状况、家庭年收入、熟人的接种状况和风险感知显著相关。
该研究强调了需要制定有针对性的沟通策略和疫苗接种干预措施。对于新开发的疫苗，解决副作用的问题更为重要。对于长期存在的疫苗，强调其有效性可以更显著地提高接种率。在提高公众信心和接种率方面，需要利用医疗保健提供者和社区影响者。清晰的沟通和社区参与是解决公众关注和错误信息的关键策略，特别是在关注加剧时期。
