Zhou Wenyue, Yang Zheng, Han Jiajun, Chen Xingping, Zou Tiande, You Jinming, Chen Jun
Jiangxi Province Key Laboratory of Animal Nutrition and Feed, Jiangxi Province Key Innovation Center of Integration in Production and Education for High-Quality and Safe Livestock and Poultry, Jiangxi Agricultural University, Nanchang 330045, China.
Animals (Basel). 2024 Sep 6;14(17):2599. doi: 10.3390/ani14172599.
The antioxidant and immune systems of weaned piglets are not fully mature and are also subjected to serious stress challenges related to oxidative stress and inflammation. Selenium (Se) is an essential element for pigs, with documented roles encompassing antioxidative and anti-inflammatory properties via selenoproteins. Sodium selenite and Se-enriched yeast are commonly acknowledged as conventional sources of Se for piglets. In the past decade, several novel Se sources have emerged in the field of weaned piglet nutrition. In this review, we will initially outline the historical timeline of Se sources as reported in weaned piglet nutrition. Afterwards, our attention will turn towards the nutritional regulation of Se sources in relation to the antioxidant and anti-inflammatory aspects of healthy weaned piglets. Ultimately, we will provide a detailed review highlighting the potential of emerging Se sources in alleviating various adverse effects of stress challenges faced by weaned piglets. These challenges include oxidative stress, enterotoxigenic infection, lipopolysaccharide-induced inflammation, heat stress, and exposure to feed mycotoxins. The output of this review will emphasize the fundamental importance of incorporating emerging Se sources in the diet of weaned piglets.
断奶仔猪的抗氧化和免疫系统尚未完全成熟，还会面临与氧化应激和炎症相关的严重应激挑战。硒（Se）是猪必需的元素，有文献记载其通过硒蛋白发挥抗氧化和抗炎特性。亚硒酸钠和富硒酵母通常被认为是仔猪常用的硒源。在过去十年中，断奶仔猪营养领域出现了几种新型硒源。在这篇综述中，我们首先将概述断奶仔猪营养中报道的硒源历史 timeline。之后，我们将把注意力转向硒源在健康断奶仔猪抗氧化和抗炎方面的营养调控。最后，我们将进行详细综述，突出新型硒源在减轻断奶仔猪面临的各种应激挑战不利影响方面的潜力。这些挑战包括氧化应激、产肠毒素感染、脂多糖诱导的炎症、热应激以及接触饲料霉菌毒素。本综述的成果将强调在断奶仔猪日粮中添加新型硒源的根本重要性。
