Wang Linzhe, Hu Jingfang, Wei Wensong, Song Yu, Li Yansheng, Gao Guowei, Zhang Chunhui, Fu Fangting
Beijing Key Laboratory of Sensor, Beijing Information Science & Technology University, Beijing 100101, China.
Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agricultural Product Processing, Ministry of Agriculture, Beijing 100193, China.
Polymers (Basel). 2024 Sep 8;16(17):2540. doi: 10.3390/polym16172540.
In this paper, we developed a paper-based fluorescent sensor using functional composite materials composed of graphene quantum dots (GQDs) coated with molecularly imprinted polymers (MIPs) for the selective detection of tetracycline (TC) in water. GQDs, as eco-friendly fluorophores, were chemically grafted onto the surface of paper fibers. MIPs, serving as the recognition element, were then wrapped around the GQDs via precipitation polymerization using 3-aminopropyltriethoxysilane (APTES) as the functional monomer. Optimal parameters such as quantum dot concentration, grafting time, and elution time were examined to assess the sensor's detection performance. The results revealed that the sensor exhibited a linear response to TC concentrations in the range of 1 to 40 µmol/L, with a limit of detection (LOD) of 0.87 µmol/L. When applied to spiked detection in actual water samples, recoveries ranged from 103.3% to 109.4%. Overall, this paper-based fluorescent sensor (MIPs@GQDs@PAD) shows great potential for portable, multi-channel, and rapid detection of TC in water samples in the future.
在本文中，我们开发了一种基于纸张的荧光传感器，该传感器使用由涂覆有分子印迹聚合物（MIP）的石墨烯量子点（GQD）组成的功能复合材料，用于选择性检测水中的四环素（TC）。作为环保型荧光团的GQD通过化学方法接枝到纸纤维表面。然后，以3-氨丙基三乙氧基硅烷（APTES）作为功能单体，通过沉淀聚合将作为识别元件的MIP包裹在GQD周围。研究了量子点浓度、接枝时间和洗脱时间等最佳参数，以评估传感器的检测性能。结果表明，该传感器对1至40 µmol/L范围内的TC浓度呈现线性响应，检测限（LOD）为0.87 µmol/L。当应用于实际水样的加标检测时，回收率在103.3%至109.4%之间。总体而言，这种基于纸张的荧光传感器（MIPs@GQDs@PAD）在未来对水样中的TC进行便携式、多通道和快速检测方面显示出巨大潜力。
