Research Center for Biomass and Bioproducts, National Research and Innovation Agency of Indonesia (BRIN), Cibinong 16911, Indonesia; Research Collaboration Center for Biomass and Biorefinery, Padjajaran Science and Technopark, Jl. Ir. Soekarno, Km.21, Jatinangor 45363, Indonesia; Research Collaboration Center for Nanocellulose, BRIN - UNAND, Padang 25163, Indonesia; Cellulosic and Functional Materials Research Centre, Universitas Sumatera Utara, Jl. Bioteknologi No.1, Medan 20155, Indonesia.
Program Studi Kimia, Jurusan Sains, Institut Teknologi Sumatera, Jalan Terusan Ryacudu, Way Hui, Jati Agung, Lampung Selatan 35365, Indonesia.
Int J Biol Macromol. 2024 Nov;279(Pt 4):135602. doi: 10.1016/j.ijbiomac.2024.135602. Epub 2024 Sep 12.
Bacterial cellulose (BC) has gained significant attention as a base material for wound dressings due to its superior physical properties, biocompatibility, and non-toxicity. However, to produce wound dressings that actively facilitate wound healing, BC modification is essential. To provide a comprehensive analysis of the potential research developments and the trends in bacterial cellulose-based wound dressings (BCWD), this review focuses on the BCWD research conducted in the last decade. The review highlights the optimization of BC usage as a base material for active wound dressing, including the incorporation of miscellaneous materials and the enhancement of BC properties such as ultra-transparency, anti-leakage, stretchability/flexibility, adhesiveness, conductivity, injectability, pattern, and pH-sensor ability.
细菌纤维素(BC)因其出色的物理性能、生物相容性和无毒特性,已成为备受关注的伤口敷料基础材料。然而,要生产出能积极促进伤口愈合的伤口敷料,就必须对 BC 进行改性。为了全面分析基于细菌纤维素的伤口敷料(BCWD)的潜在研究进展和趋势,本综述重点关注了过去十年中对 BCWD 的研究。本综述强调了将 BC 优化为活性伤口敷料基础材料的使用,包括将各种材料纳入其中,并增强 BC 的性能,如超高透明度、防漏性、拉伸性/柔韧性、粘附性、导电性、可注射性、图案和 pH 传感器能力。