四肢瘫痪作为系统性红斑狼疮合并肺动脉高压的首发症状。
Tetraplegia as a presenting feature of systemic lupus erythematosus complicated by pulmonary hypertension.
作者信息
Hardie R J, Isenberg D A
出版信息
Ann Rheum Dis. 1985 Jul;44(7):491-3. doi: 10.1136/ard.44.7.491.
Abstract
A 28-year-old woman presenting with subacute onset of a tetraplegia is described who was shown to have active systemic lupus erythematosus in association with high circulating anticardiolipin binding and lupus anticoagulant activity. The patient later developed severe symptomatic systemic and pulmonary hypertension and required emergency resuscitation. This case provides further support for an association between antiphospholipid antibodies and the clinical features of central nervous system (CNS) involvement and pulmonary hypertension in SLE.
摘要
本文描述了一名28岁亚急性起病的四肢瘫痪女性患者，该患者被证实患有活动性系统性红斑狼疮，伴有高循环抗心磷脂结合及狼疮抗凝物活性。患者后来出现严重的症状性系统性和肺动脉高压，需要紧急复苏。该病例进一步支持了抗磷脂抗体与系统性红斑狼疮中枢神经系统受累及肺动脉高压临床特征之间的关联。
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