迪戈斯病：与抗心磷脂抗体及狼疮抗凝物的关联。
Degos' disease: association with anticardiolipin antibodies and the lupus anticoagulant.
作者信息
Englert H J, Hawkes C H, Boey M L, Derue G J, Loizou S, Harris E N, Gharavi A E, Hull R G, Hughes G R
出版信息
Br Med J (Clin Res Ed). 1984 Sep 8;289(6445):576. doi: 10.1136/bmj.289.6445.576.
Abstract
A woman presented with multiple cerebral thromboses and skin lesions characteristic of Degos' disease. Her serum contained high titres of anticardiolipin antibodies and showed lupus anticoagulant activity, both known to be strong markers of a thrombotic tendency in systemic lupus erythematosus. This finding may have therapeutic implications for this usually fatal disease.
摘要
一名女性出现多发性脑梗死及具有德戈斯病特征的皮肤损害。她的血清中抗心磷脂抗体滴度很高，且显示出狼疮抗凝物活性，这两者均为系统性红斑狼疮中血栓形成倾向的有力标志物。这一发现可能对这种通常致命的疾病具有治疗意义。
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