Gacic Jasna M, Rascanin Sanja R, Jovanovic Mirjana R, Nikolovski Srdjan S, Jovanovic Nina, Petkovic Jelena, Zdravkovic Nebojsa, Djokic Olivera, Rancic Nemanja K
Surgery, Clinical Hospital Center "Bezanijska kosa", School of Medicine, University of Belgrade, Belgrade, SRB.
Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SRB.
Cureus. 2024 Aug 13;16(8):e66821. doi: 10.7759/cureus.66821. eCollection 2024 Aug.
Induced pluripotent stem cells (iPSCs) are derived by reprogramming adult somatic cells using a forced expression of four specific transcription factors in a highly controlled artificial environment. The aim of this paper is to examine the knowledge about these cells of the general population and the population of health workers in relation to gender.
The research was designed as a cohort study conducted with a validated questionnaire to assess knowledge about iPSCs. Respondents were people over 18 years of age on the territory of the cities of Belgrade and Kragujevac in Serbia.
The study surveyed a total of 1,047 respondents, 560 (53.5%) women and 487 (46.5%) men. Statistically significant differences were observed for both genders. Women from both populations were better informed, more often agreed to treatment with iPSCs, more often supported further research, and were willing to take further education about iPSCs.
Comparing men and women from both populations, we found that men and women health workers showed greater knowledge compared to the general population. Level of knowledge and attitudes of the public can have multiple effects on further research emphasizing the importance of the support of public opinion about this type of treatment.
诱导多能干细胞(iPSCs)是通过在高度可控的人工环境中强制表达四种特定转录因子,对成人体细胞进行重编程而获得的。本文旨在研究普通人群和医护人员群体对这些细胞的了解情况,并探讨性别差异。
本研究设计为一项队列研究,采用经过验证的问卷来评估对iPSCs的了解程度。调查对象为塞尔维亚贝尔格莱德市和克拉古耶瓦茨市18岁以上的人群。
该研究共调查了1047名受访者,其中女性560人(53.5%),男性487人(46.5%)。两性之间均观察到具有统计学意义的差异。两个群体中的女性了解情况更好,更常同意接受iPSCs治疗,更常支持进一步研究,并且愿意接受关于iPSCs的继续教育。
比较两个群体中的男性和女性,我们发现医护人员群体中的男性和女性比普通人群表现出更丰富的知识。公众的知识水平和态度可能对进一步研究产生多种影响,这凸显了公众舆论对这类治疗支持的重要性。