Cornaggia C, Canevini M P, Giuccioli D, Pinelli P, Pruneri C, Canger R
Ital J Neurol Sci. 1985 Jun;6(2):201-5. doi: 10.1007/BF02229193.
A retrospective survey on 66 adults with epilepsy who received multiple drug therapy after the failure of single drugs showed: a reduction of seizure frequency of 75% or more in 16.5%, no change in 67% and an increase in seizure frequency of 100% or more in 16.5%. Multiple drug therapy is of limited value in severe epilepsies.
一项针对66名癫痫成人患者的回顾性调查显示,这些患者在单药治疗失败后接受了多种药物联合治疗:16.5%的患者癫痫发作频率降低了75%或更多,67%的患者无变化,16.5%的患者癫痫发作频率增加了100%或更多。多种药物联合治疗对严重癫痫的价值有限。