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微生物组多组学可以加速人类粪便堆肥研究。

Microbiome multi-omics can accelerate human excrement composting research.

机构信息

Center for Applied Microbiome Science, Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ, USA.

Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ, USA.

出版信息

Microbiome. 2024 Sep 16;12(1):174. doi: 10.1186/s40168-024-01894-x.

DOI:10.1186/s40168-024-01894-x
PMID:39285488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11403854/
Abstract

In this editorial, we discuss the need for a new, long-term strategy for managing human excrement (feces and urine) to facilitate health equity and promote environmental sustainability. Human excrement composting (HEC), a human-directed process driven by highly variable and diverse microbiomes, provides a means to advance this need and we discuss how microbiome science can help to advance HEC research. We argue that the technological advancements that have driven the growth of microbiome science, including microbiome and untargeted metabolome profiling, can be leveraged to enhance our understanding of safe and efficient HEC. We conclude by presenting our perspective on how we can begin applying these technologies to develop accessible procedures for safe HEC. Video Abstract.

摘要

在这篇社论中,我们讨论了制定新的、长期的人类粪便(粪便和尿液)管理策略的必要性,以促进健康公平和环境可持续性。人类粪便堆肥(HEC)是一种由高度可变和多样化的微生物组驱动的人为过程,为满足这一需求提供了一种手段,我们讨论了微生物组科学如何帮助推进 HEC 研究。我们认为,推动微生物组科学发展的技术进步,包括微生物组和非靶向代谢组学分析,可以用来提高我们对安全高效 HEC 的理解。最后,我们提出了我们的观点,即如何开始应用这些技术来开发安全 HEC 的可访问程序。视频摘要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2451/11403854/1ba79278d89c/40168_2024_1894_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2451/11403854/1ba79278d89c/40168_2024_1894_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2451/11403854/1ba79278d89c/40168_2024_1894_Fig1_HTML.jpg

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Bioresour Technol. 2024 Feb;393:130118. doi: 10.1016/j.biortech.2023.130118. Epub 2023 Nov 27.
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Inadvertent human genomic bycatch and intentional capture raise beneficial applications and ethical concerns with environmental DNA.环境 DNA 技术在无意间捕获人类基因组序列和有目的地捕获人类基因组序列时引发了有益应用和伦理问题。
Nat Ecol Evol. 2023 Jun;7(6):873-888. doi: 10.1038/s41559-023-02056-2. Epub 2023 May 15.
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Succession of Microbial Community during the Co-Composting of Food Waste Digestate and Garden Waste.
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Int J Environ Res Public Health. 2022 Aug 12;19(16):9945. doi: 10.3390/ijerph19169945.
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Quality assessment, safety evaluation, and microbiome analysis of night-soil compost from Lahaul valley of northwestern Himalaya.青藏高原拉霍尔山谷粪便堆肥的质量评估、安全性评价和微生物组分析。
Waste Manag. 2022 Jul 15;149:42-52. doi: 10.1016/j.wasman.2022.06.003. Epub 2022 Jun 14.
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Profiles of antibiotic- and heavy metal-related resistance genes in animal manure revealed using a metagenomic analysis.利用宏基因组分析揭示动物粪便中抗生素和重金属相关抗性基因的特征。
Ecotoxicol Environ Saf. 2022 Jul 1;239:113655. doi: 10.1016/j.ecoenv.2022.113655. Epub 2022 May 24.
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