State Grid Shandong Electric Power Research Institute, Jinan, China.
State Grid Shandong Electric Power Company, Jinan, China.
Luminescence. 2024 Sep;39(9):e4886. doi: 10.1002/bio.4886.
A novel seminaphthorhodafluor-based fluorescent probe was designed and prepared. It exhibited an outstanding off-on fluorescence response (about 45-fold enhancement) to Cu because the structure changed from a spirocyclic form to a ring-open state. It showed satisfactory detection performances for Cu with fast response speed, high selectivity and anti-interference, and a low detection limit (22.9 nM) due to its long emission wavelength and off-on fluorescence response mode. This probe was also satisfactorily applied for the monitoring of Cu in living cells and zebrafish.
设计并制备了一种基于新型半萘并[1,8-d,f]氧杂蒽的荧光探针。由于结构从螺环形式转变为开环状态，该探针对 Cu 表现出出色的关-开荧光响应（约 45 倍增强）。由于其长发射波长和关-开荧光响应模式，该探针对 Cu 具有快速的响应速度、高选择性和抗干扰性以及低检测限（22.9 nM），表现出令人满意的检测性能。该探针还可满意地用于活细胞和斑马鱼中 Cu 的监测。
