Zhang Lu-Yuan, Jiang Ming-Zhu, Li Dong-Mei, Gong Ya-Qin, Xia Yun-Yu, Wang Xiao-Chun, Lin Chen, Yan Shan-Jun, Lu Rong-Zhu, Li Chong
Department of Neurology, Kunshan First People's Hospital/ Affiliated Kunshan Hospital to Jiangsu University, Kunshan, Suzhou, China.
Office of Medical Ethics, Department of Scientific and Technological Talents, Kunshan First People's Hospital, Suzhou, China.
Dose Response. 2024 Sep 16;22(3):15593258241282768. doi: 10.1177/15593258241282768. eCollection 2024 Jul-Sep.
This study aimed to explore the relationship between climatic parameters and the daily cases of Bell's palsy (BP) among hospital outpatients, providing ecological evidence for understanding BP etiology and prevention.
Retrospective analysis was conducted on data from 2187 BP patients who attended Kunshan First People's Hospital Outpatient Clinic from January 1, 2020, to December 31, 2022. Meteorological data, including temperature, relative humidity, precipitation, wind speed, sunshine duration, and atmospheric pressure, were collected and combined with daily BP case records. Additionally, air quality index was used as a covariate.
The number of new BP cases among outpatients showed a negative correlation with average daily temperature. A nonlinear relationship between daily average temperature and BP cases was observed through the generalized additive model (GAM). A significant negative correlation was identified between daily average temperature and BP cases, with inflection points at temperatures above 4.2°C, suggesting a potential decrease in BP risk with temperature rise beyond this threshold.
This study provides ecological evidence of a link between climatic factors and BP occurrence. Temperature demonstrated a significant nonlinear negative correlation with daily BP incidence, highlighting temperature and cold exposure as key targets for BP prevention in Kunshan.
本研究旨在探讨气候参数与医院门诊中贝尔麻痹（BP）每日病例数之间的关系，为理解BP病因及预防提供生态学证据。
对2020年1月1日至2022年12月31日在昆山市第一人民医院门诊就诊的2187例BP患者的数据进行回顾性分析。收集了包括温度、相对湿度、降水量、风速、日照时长和大气压力在内的气象数据，并与每日BP病例记录相结合。此外，将空气质量指数用作协变量。
门诊中新发BP病例数与日平均温度呈负相关。通过广义相加模型（GAM）观察到日平均温度与BP病例之间存在非线性关系。日平均温度与BP病例之间存在显著负相关，在温度高于4.2°C时出现拐点，这表明温度超过该阈值时BP风险可能降低。
本研究提供了气候因素与BP发生之间存在关联的生态学证据。温度与每日BP发病率呈显著非线性负相关，突出了温度和寒冷暴露是昆山BP预防的关键目标。
