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匈牙利贝尔氏面瘫流行病学中的季节性模式。

Seasonal patterns in the epidemiology of Bell's palsy in Hungary.

作者信息

Varga Eszter, Battamir Ulambayar, Szegedi István, Hudák Lilla, Kovács Nóra, Nagy Attila Csaba

机构信息

Department of Neurology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Department of Health Informatics, Faculty of Health Sciences, University of Debrecen, Debrecen, Hungary.

出版信息

Front Neurol. 2023 Jun 20;14:1188137. doi: 10.3389/fneur.2023.1188137. eCollection 2023.

DOI:10.3389/fneur.2023.1188137
PMID:37409014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10318583/
Abstract

INTRODUCTION

Epidemiological data on Bell's palsy are vital for elucidating disease prevalence and enhancing therapeutic options. Our objective was to explore the prevalence and possible risk factors associated with Bell's palsy recurrence in the Clinical Center of the University of Debrecen service area. Secondary data analysis was performed using hospital discharge data, including patient information and comorbidities.

METHODS

Data was obtained from the Clinical Center of the University of Debrecen, on Bell's palsy patients who were treated at the hospital between January 1, 2015 and December 31, 2021. Multiple logistic regression analysis was used to examine the factors associated with Bell's palsy recurrence.

RESULTS

Of the 613 patients analyzed, 5.87% had recurrent paralysis, and the median time interval between episodes was 315 days. Hypertension was significantly associated with Bell's palsy recurrence. Moreover, seasonal distribution analysis revealed that the number of Bell's palsy episodes was higher in colder seasons, with spring and winter having a significantly higher number of episodes than summer and autumn.

DISCUSSION

This study provides insights into the prevalence and associated risk factors of Bell's palsy recurrence, which could aid in its management and help reduce the long-term consequences of the disease. Further research is necessary to determine the precise mechanisms underlying these findings.

摘要

引言

关于贝尔麻痹的流行病学数据对于阐明疾病患病率和增加治疗选择至关重要。我们的目标是在德布勒森大学临床中心服务区探讨贝尔麻痹复发的患病率及可能的危险因素。使用包括患者信息和合并症在内的医院出院数据进行二次数据分析。

方法

数据取自德布勒森大学临床中心,涉及2015年1月1日至2021年12月31日期间在该医院接受治疗的贝尔麻痹患者。采用多元逻辑回归分析来检查与贝尔麻痹复发相关的因素。

结果

在分析的613例患者中,5.87%出现了麻痹复发,发作之间的中位时间间隔为315天。高血压与贝尔麻痹复发显著相关。此外,季节分布分析显示,贝尔麻痹发作次数在较冷季节较多,春季和冬季的发作次数明显高于夏季和秋季。

讨论

本研究为贝尔麻痹复发的患病率及相关危险因素提供了见解,这有助于其管理并有助于减少该疾病的长期后果。有必要进行进一步研究以确定这些发现背后的精确机制。

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本文引用的文献

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J Clin Med. 2022 Jan 14;11(2):427. doi: 10.3390/jcm11020427.
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Population-based study and a scoping review for the epidemiology and seasonality in and effect of weather on Bell's palsy.基于人群的研究和范围综述,探讨贝尔氏麻痹的流行病学和季节性以及天气对其的影响。
Sci Rep. 2021 Aug 20;11(1):16941. doi: 10.1038/s41598-021-96422-4.
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Evaluation of Effects of Diabetes Mellitus, Hypercholesterolemia and Hypertension on Bell's Palsy.
温度和气压对杭州贝尔麻痹发病率的影响:分布滞后非线性分析。
Sci Rep. 2023 Nov 22;13(1):20424. doi: 10.1038/s41598-023-47570-2.
糖尿病、高胆固醇血症和高血压对贝尔麻痹影响的评估。
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Epidemiological trends of Bell's palsy treated with steroids in Korea between 2008 and 2018.2008 年至 2018 年韩国使用类固醇治疗贝尔麻痹的流行病学趋势。
Muscle Nerve. 2021 Jun;63(6):845-851. doi: 10.1002/mus.27213. Epub 2021 Mar 13.
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The psychosocial impact of facial palsy: A systematic review.面瘫的社会心理影响:系统评价。
Br J Health Psychol. 2020 Sep;25(3):695-727. doi: 10.1111/bjhp.12440. Epub 2020 Jun 15.
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Quality of Life in Bell's Palsy: Correlation with Sunnybrook and House-Brackmann Over Time.贝尔麻痹患者的生活质量:与 Sunnybrook 和 House-Brackmann 随时间的相关性。
Laryngoscope. 2021 Feb;131(2):E612-E618. doi: 10.1002/lary.28751. Epub 2020 May 28.
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