Hans Berger Department of Neurology, Jena,
Department of Neurology, Neuruppin,
Neuroepidemiology. 2018;51(3-4):207-215. doi: 10.1159/000492671. Epub 2018 Sep 11.
To evaluate if weather or changes in weather are risk factors for Bell's palsy (BP) as exposure to draught of cold air has been popularly associated with the occurrence of BP.
Using a multicenter hospital-based case-crossover study, we analyzed the association between ambient temperature, atmospheric pressure, relative air humidity or their 24 h changes and the risk for BP in 825 patients or subgroups.
One day following a 24 h increase in atmospheric pressure of more than 6 hPa, the risk for BP increased by 35% (OR 1.35; 95% CI 1.03-1.78) in the overall population. The risk for BP more than doubled in patients with diabetes mellitus after rapid variations in ambient temperature, independent of the direction (temperature decrease > 2.25°C; OR 2.15; 95% CI 1.08-4.25; temperature increase between 0.75 and 2.25°C; OR 2.88; 95% CI 1.63-5.10).
Our findings support the hypothesis of an association between certain weather conditions and the risk for BP with acute changes in atmospheric pressure and ambient temperature as the main risk factors. Additionally, contrasting results for risk of BP after temperature changes in the diabetic and non-diabetic subgroups support the paradigm of a diabetic facial palsy as a distinct disease entity.
评估天气或天气变化是否是贝尔麻痹（BP）的危险因素，因为暴露于冷空气 draught 已被普遍认为与 BP 的发生有关。
我们采用多中心基于医院的病例交叉研究，分析了环境温度、大气压、相对空气湿度或其 24 小时变化与 825 例患者或亚组的 BP 风险之间的关系。
在大气压力增加超过 6 hPa 的 24 小时后一天，总体人群中 BP 的风险增加了 35%（OR 1.35；95%CI 1.03-1.78）。在快速变化的环境温度下，糖尿病患者的 BP 风险增加了一倍以上，与温度变化的方向无关（温度下降>2.25°C；OR 2.15；95%CI 1.08-4.25；温度升高 0.75-2.25°C；OR 2.88；95%CI 1.63-5.10）。
我们的研究结果支持了某些天气条件与 BP 风险之间存在关联的假设，大气压力和环境温度的急性变化是主要的危险因素。此外，糖尿病亚组和非糖尿病亚组在温度变化后发生 BP 风险的对比结果支持了糖尿病性面瘫作为一种独特疾病实体的概念。
