Zhao Yan, Xia Qiuqiu, Zhu Lu, Xia Jiyue, Xiang Shaojie, Mao Qiming, Dong Huaize, Weng Zijing, Liao Wenbo, Xin Zhijun
Department of Orthopedic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, Guizhou, China.
Institut Curie, PSL Research University, CNRS UMR3244, Dynamics of Genetic Information, Sorbonne Université, 75005, Paris, France.
Heliyon. 2024 Aug 28;10(17):e36509. doi: 10.1016/j.heliyon.2024.e36509. eCollection 2024 Sep 15.
Intervertebral disc degeneration (IDD) is a chronic disabling disease caused by degeneration of nucleus pulposus cells, decreased activity and the number of nucleus pulposus cells, decreased extracellular matrix, and infiltration of inflammatory factors, resulting in low back and leg pain. Recent studies have shown that non-surgical treatment is of great significance in reversing the progression of degenerative disc disease, and there are more relevant literature reports. However, there is no bibliometric analysis in this area. This study aimed to describe the knowledge structure and thematic trends of non-surgical treatment methods for IDD through bibliometrics.
Articles and reviews on non-surgical treatment of disc degeneration from 1998 to 2022 were collected on the Web of Science. VOSviewer 1.6.18, CiteSpace 6.1.R3, R package "bibliometrix" and two online analysis platforms were used for bibliometric and visual literature analysis.
961 articles were screened for inclusion, including 821 articles and 140 reviews. The analysis of our study shows that publications in the non-surgical treatment of disc degeneration are increasing annually, with publications coming mainly from North America and Asia, with China and the United States dominating. Huazhong Univ Sci & Technol and Wang K are the most prolific institutions and authors, respectively, and Le Maitre CL is the most co-cited author. However, there is less collaboration between institutions in different countries. is both the most published and the most cited journal. According to the co-citation and co-occurrence analysis results, "mesenchymal stem cells," "exosomes," "medication," and "tissue engineering" are the current research hotspots in this field.
This study employs bibliometric analysis to explore the knowledge structure and trends of non-surgical treatments for IDD from 2013 to 2022. Key research hotspots include mesenchymal stem cells, exosomes, medication, and tissue engineering. The number of publications, especially from China and the USA, has increased significantly, though international collaboration needs improvement. Influential contributors include Wang K and the journal Spine. These findings provide a comprehensive overview and highlight important future directions for the field.
椎间盘退变（IDD）是一种慢性致残性疾病，由髓核细胞退变、髓核细胞活性和数量减少、细胞外基质减少以及炎症因子浸润引起，导致腰腿痛。最近的研究表明，非手术治疗在逆转退行性椎间盘疾病进展方面具有重要意义，且有更多相关文献报道。然而，该领域尚无文献计量学分析。本研究旨在通过文献计量学描述IDD非手术治疗方法的知识结构和主题趋势。
在科学网收集1998年至2022年关于椎间盘退变非手术治疗的文章和综述。使用VOSviewer 1.6.18、CiteSpace 6.1.R3、R包“bibliometrix”和两个在线分析平台进行文献计量和可视化文献分析。
筛选出961篇纳入文章，其中包括821篇论文和140篇综述。我们的研究分析表明，椎间盘退变非手术治疗方面的出版物数量逐年增加，出版物主要来自北美和亚洲，中国和美国占主导地位。华中科技大学和王坤分别是发文量最多的机构和作者，勒梅特尔·C·L是被引次数最多的作者。然而，不同国家机构之间的合作较少。《脊柱》既是发文量最多也是被引次数最多的期刊。根据共被引和共现分析结果，“间充质干细胞”“外泌体”“药物治疗”和“组织工程”是该领域当前的研究热点。
本研究采用文献计量学分析方法，探索2013年至2022年IDD非手术治疗的知识结构和趋势。主要研究热点包括间充质干细胞、外泌体、药物治疗和组织工程。出版物数量显著增加，尤其是来自中国和美国的，但国际合作仍需改进。有影响力的贡献者包括王坤和《脊柱》杂志。这些发现为该领域提供了全面概述，并突出了重要的未来研究方向。
