Department of Bone and Joint Surgery, Research Centre for Regenerative Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Guangxi Diabetic Foot Salvage Engineering Research Center, Guangxi Medical University, Nanning, China.
Front Endocrinol (Lausanne). 2022 Jul 22;13:922070. doi: 10.3389/fendo.2022.922070. eCollection 2022.
Osteoblasts-Osteoclasts has been a major area in bone disease research for a long time. However, there are few systematic studies in this field using bibliometric analysis. We aimed to perform a bibliometric analysis and visualization study to determine hotspots and trends of osteoblasts-osteoclasts in bone diseases, identify collaboration and influence among authors, countries, institutions, and journals, and assess the knowledge base to develop basic and clinical research in the future.
We collected articles and reviews for osteoblasts-osteoclasts in bone diseases from the Web of Science Core Collection. In addition, we utilized scientometrics software (CiteSpace5.8 and VOSviewer1.6.18) for visual analysis of countries/regions, institutions, authors, references, and keywords in the field.
In total, 16,832 authors from 579 institutions in 73 countries/regions have published 3,490 papers in 928 academic journals. The literature in this field is rapidly increasing, with publishing the most articles, whereas J had the most co-cited journals. These two journals mainly focused on molecular biology and the clinical medicine domain. The countries with the highest number of publications were the US and China, and the University of Arkansas for Medical Sciences was the most active institution. Regarding authors, Stavros C. Manolagas published the most articles, and Hiroshi Takayanagi had the most co-cited papers. Research in this field mainly includes molecular expression and regulatory mechanisms, differentiation, osteoprotection, inflammation, and tumors. The latest research hotspots are oxidative stress, mutation, osteocyte formation and absorption, bone metabolism, tumor therapy, and in-depth mechanisms.
We identified the research hotspots and development process of osteoblasts-osteoclasts in bone disease using bibliometric and visual methods. Osteoblasts-osteoclasts have attracted increasing attention in bone disease. This study will provide a valuable reference for researchers concerned with osteoblasts-osteoclasts in bone diseases.
成骨细胞-破骨细胞一直是骨疾病研究的一个主要领域。然而，在这个领域中，使用文献计量分析进行系统研究的情况很少。我们旨在进行文献计量分析和可视化研究，以确定骨疾病中成骨细胞-破骨细胞的热点和趋势，识别作者、国家、机构和期刊之间的合作和影响，并评估知识库，以促进未来的基础和临床研究。
我们从 Web of Science 核心合集收集了骨疾病中成骨细胞-破骨细胞的文章和综述。此外，我们还利用科学计量学软件（CiteSpace5.8 和 VOSviewer1.6.18）对该领域的国家/地区、机构、作者、参考文献和关键词进行可视化分析。
共有来自 73 个国家/地区的 579 个机构的 16832 位作者在 928 种学术期刊上发表了 3490 篇论文。该领域的文献呈快速增长趋势， 发表的文章最多，而 J 拥有被引频次最高的期刊。这两种期刊主要集中在分子生物学和临床医学领域。发文数量最多的国家是美国和中国，最活跃的机构是阿肯色大学医学科学分校。就作者而言，Stavros C. Manolagas 发表的文章最多，Hiroshi Takayanagi 被引频次最高。该领域的研究主要包括分子表达和调控机制、分化、骨保护、炎症和肿瘤。最新的研究热点是氧化应激、突变、骨细胞形成和吸收、骨代谢、肿瘤治疗和深入机制。
我们使用文献计量和可视化方法确定了骨疾病中成骨细胞-破骨细胞的研究热点和发展过程。成骨细胞-破骨细胞在骨疾病中受到越来越多的关注。这项研究将为关注骨疾病中成骨细胞-破骨细胞的研究人员提供有价值的参考。
