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Checkpoint therapy in cancer treatment: progress, challenges, and future directions.

作者信息

Bicak Mesude, Cimen Bozkus Cansu, Bhardwaj Nina

机构信息

Vaccine and Cell Therapy Laboratory and.

Department of Medicine, Division of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

出版信息

J Clin Invest. 2024 Sep 17;134(18):e184846. doi: 10.1172/JCI184846.

DOI:10.1172/JCI184846
PMID:39286978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11405031/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a25c/11405031/5140c6f0b053/jci-134-184846-g148.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a25c/11405031/5140c6f0b053/jci-134-184846-g148.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a25c/11405031/5140c6f0b053/jci-134-184846-g148.jpg

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Front Oncol. 2024 Mar 20;14:1368732. doi: 10.3389/fonc.2024.1368732. eCollection 2024.
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The introduction of LAG-3 checkpoint blockade in melanoma: immunotherapy landscape beyond PD-1 and CTLA-4 inhibition.
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Int J Mol Sci. 2025 Apr 12;26(8):3669. doi: 10.3390/ijms26083669.
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Thrombospondin-1 induces immunogenic cell death in human mucoepidermoid carcinoma MC-3 cells via the PERK/eIF2α signaling pathway: potential implications for tumor immunotherapy.血小板反应蛋白-1通过PERK/eIF2α信号通路诱导人黏液表皮样癌MC-3细胞发生免疫原性细胞死亡：对肿瘤免疫治疗的潜在意义。
Discov Oncol. 2025 Apr 19;16(1):576. doi: 10.1007/s12672-025-02315-7.
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