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腭裂手术的合理风险比:新的关键分析。

Reasonable Risk Ratio of Palate Surgery: A New Critical Analysis.

机构信息

Otolaryngology, Asia Sleep Centre, Paragon, Singapore, Singapore.

General Surgery, Tan Tock Seng Hospital, Singapore, Singapore.

出版信息

J Otolaryngol Head Neck Surg. 2024 Jan-Dec;53:19160216241279074. doi: 10.1177/19160216241279074.

DOI:10.1177/19160216241279074
PMID:39287430
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11409292/
Abstract

OBJECTIVE.: A new critical complication risk analysis, the reasonable risk ratio (RRR or R) for palate surgeries in obstructive sleep apnea patients.

METHODS.: Analysis from published meta-analyses, systematic reviews on success rates, and complications encountered for 3 palate surgeries, expansion sphincter pharyngoplasty (ESP), barbed repositioning pharyngoplasty (BRP) and modified uvulopalatopharyngoplasty (mUPPP), over 20 years. The RRR is derived from a ratio of the percentage of each respective complication over the success rate of that particular surgical procedure. The benchmark RRR of tonsillectomy is set at 0.035 to 0.078. An RRR below this benchmark value is more favorable as tonsillectomy is a widely accepted ENT procedure with risks to benefit well accepted.

RESULTS.: The RRR for foreign body (FB) sensation (BRP) ranged from 0.03 to 0.23 (mean RRR of 0.14), FB sensation (ESP) 0.01, FB sensation (mUPPP) ranged from 0.33 to 0.55 (mean RRR of 0.44). The RRR for swallowing difficulties (BRP) ranged from 0.04 to 0.23 (mean RRR of 0.11), mUPPP, was 0.37; no reported swallowing difficulties with the ESP. The RRR for velopharyngeal insufficiency (VPI) (BRP) ranged from 0.009 to 0.18 (mean RRR of 0.07), and RRR VPI (mUPPP) was 0.14. The RRR (BRP) for dry throat was 0.06 and the mUPPP was 0.35, with no reported VPI or dry throat for ESP. The overall RRR for the BRP was 0.09, ESP was 0.01 and mUPPP was 0.29.

CONCLUSION.: RRR provides a summarized data-driven, statistical guide to aid decision-making, and helps in patient counseling. BRP and ESP have been shown to have less complications compared to mUPPP. IV.

摘要

目的

分析一种新的严重并发症风险,即阻塞性睡眠呼吸暂停患者行腭部手术的合理风险比(RRR 或 R)。

方法

分析 20 多年来 3 种腭部手术(扩张咽括约肌成形术(ESP)、带刺复位咽成形术(BRP)和改良悬雍垂腭咽成形术(mUPPP))的成功率和并发症的已发表荟萃分析和系统评价。RRR 是通过比较特定手术的并发症百分比与成功率得出的比值。扁桃体切除术的基准 RRR 值设定为 0.035 至 0.078。低于此基准值的 RRR 更有利,因为扁桃体切除术是一种广泛接受的耳鼻喉科手术,其风险与益处已被广泛接受。

结果

异物感(BRP)的 RRR 范围为 0.03 至 0.23(平均 RRR 为 0.14),异物感(ESP)为 0.01,异物感(mUPPP)为 0.33 至 0.55(平均 RRR 为 0.44)。吞咽困难(BRP)的 RRR 范围为 0.04 至 0.23(平均 RRR 为 0.11),mUPPP 为 0.37;ESP 无吞咽困难报告。腭咽闭合不全(VPI)(BRP)的 RRR 范围为 0.009 至 0.18(平均 RRR 为 0.07),mUPPP 的 RRR 为 0.14。BRP 组的咽干 RRR 为 0.06,mUPPP 组为 0.35,ESP 组无 VPI 或咽干报告。BRP 的总体 RRR 为 0.09,ESP 为 0.01,mUPPP 为 0.29。

结论

RRR 提供了一种数据驱动的总结,有助于做出决策,并为患者咨询提供帮助。与 mUPPP 相比,BRP 和 ESP 的并发症较少。IV。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03e9/11409292/c8939761e087/10.1177_19160216241279074-img2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03e9/11409292/c8939761e087/10.1177_19160216241279074-img2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03e9/11409292/c8939761e087/10.1177_19160216241279074-img2.jpg

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本文引用的文献

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Expansion sphincter pharyngoplasty in OSA: a 15 year review.扩张咽缩肌成形术治疗阻塞性睡眠呼吸暂停:15 年回顾。
Eur Arch Otorhinolaryngol. 2023 Jul;280(7):3337-3344. doi: 10.1007/s00405-023-07901-5. Epub 2023 Mar 2.
2
Complications and side effects after barbed pharyngoplasty: a systematic review.经皮咽成形术后的并发症和副作用:系统评价。
Sleep Breath. 2023 Mar;27(1):31-38. doi: 10.1007/s11325-022-02585-3. Epub 2022 Feb 25.
3
Barbed pharyngoplasty for obstructive sleep apnea: A meta-analysis.有倒刺的咽成形术治疗阻塞性睡眠呼吸暂停:一项荟萃分析。
Am J Otolaryngol. 2022 Mar-Apr;43(2):103306. doi: 10.1016/j.amjoto.2021.103306. Epub 2021 Dec 3.
4
Barbed Reposition Pharyngoplasty versus Expansion Sphincter Pharyngoplasty: A Meta-Analysis.有刺再定位咽成形术与扩张括约肌咽成形术的比较:一项荟萃分析。
Laryngoscope. 2021 Jun;131(6):1420-1428. doi: 10.1002/lary.29357. Epub 2020 Dec 25.
5
Long-Term Subjective Outcomes of Barbed Reposition Pharyngoplasty for Obstructive Sleep Apnea Syndrome Treatment.巴宾斯基再定位咽成形术治疗阻塞性睡眠呼吸暂停综合征的长期主观疗效。
Int J Environ Res Public Health. 2020 Feb 27;17(5):1542. doi: 10.3390/ijerph17051542.
6
Long-term Complications of Palate Surgery: A Multicenter Study of 217 Patients.腭裂手术的长期并发症:217 例患者的多中心研究。
Laryngoscope. 2020 Sep;130(9):2281-2284. doi: 10.1002/lary.28432. Epub 2019 Nov 25.
7
Long-term Efficacy of Uvulopalatopharyngoplasty among Adult Patients with Obstructive Sleep Apnea: A Systematic Review and Meta-analysis.成人阻塞性睡眠呼吸暂停患者悬雍垂腭咽成形术的长期疗效:系统评价和荟萃分析。
Otolaryngol Head Neck Surg. 2019 Sep;161(3):401-411. doi: 10.1177/0194599819840356. Epub 2019 Jun 11.
8
Long-Term Incidence of Velopharyngeal Insufficiency and Other Sequelae following Uvulopalatopharyngoplasty.悬雍垂腭咽成形术后腭咽闭合不全及其他后遗症的长期发生率
Otolaryngol Head Neck Surg. 2017 Apr;156(4):606-610. doi: 10.1177/0194599816688646. Epub 2017 Jan 24.
9
Phenotypic approaches to obstructive sleep apnoea - New pathways for targeted therapy.表型方法治疗阻塞性睡眠呼吸暂停——靶向治疗的新途径。
Sleep Med Rev. 2018 Feb;37:45-59. doi: 10.1016/j.smrv.2016.12.003. Epub 2016 Dec 18.
10
Barbed reposition pharyngoplasty (BRP) for OSAHS: a feasibility, safety, efficacy and teachability pilot study. "We are on the giant's shoulders".用于阻塞性睡眠呼吸暂停低通气综合征的倒刺复位咽成形术(BRP):一项可行性、安全性、有效性及可教授性的初步研究。“我们站在巨人的肩膀上” 。
Eur Arch Otorhinolaryngol. 2015 Oct;272(10):3065-70. doi: 10.1007/s00405-015-3628-3. Epub 2015 Apr 12.