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有刺再定位咽成形术与扩张括约肌咽成形术的比较:一项荟萃分析。

Barbed Reposition Pharyngoplasty versus Expansion Sphincter Pharyngoplasty: A Meta-Analysis.

机构信息

Department of Otolaryngology, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.

Department of Preventive and Social Medicine, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.

出版信息

Laryngoscope. 2021 Jun;131(6):1420-1428. doi: 10.1002/lary.29357. Epub 2020 Dec 25.

Abstract

OBJECTIVE

This study was to compare barbed reposition pharyngoplasty (BRP) and expansion sphincter pharyngoplasty (ESP) in the treatment of obstructive sleep apnea (OSA).

METHODS

Relevant 907 articles were searched from various databases until August 2020, including PubMed, MEDLINE, EMBASE, Cochrane Library, Web of Science and Scopus, and reference lists.

RESULTS

Four studies with a total of 208 participants were included. The mean reduction of apnea-hypopnea index (AHI) in the BRP group was 74.03% and the mean reduction of AHI in the ESP group was 60.17%. The mean success rate in the BRP group and the ESP group was 84.96% and 79.87%, respectively. The mean difference (MD) of the change in AHI between groups was not significantly different (MD = -1.24 event/hr, 95% CI [-11.86, 9.36], P = .82). There was no significant difference in postoperative AHI, postoperative Epworth Sleepiness Scale, pain, hospital stay, time to oral diet, and the change in oxygen desaturation index in both groups whereas the analgesic requirement was lower in the BRP group. Operative time was lower in the BRP group (MD = 21.72 minutes, 95% CI [18.85, 24.60], P < .0001).

CONCLUSION

The outcomes in both procedures are comparable in the improvement of OSA with palatal collapse. BRP is superior to ESP in term of surgical time. However, randomized clinical controlled trials with multicenter cooperation and long-term follow-up are essential to further demonstrate the efficacy of these procedures. Laryngoscope, 131:1420-1428, 2021.

摘要

目的

本研究旨在比较带刺再定位咽成形术(BRP)和扩张括约肌咽成形术(ESP)治疗阻塞性睡眠呼吸暂停(OSA)的效果。

方法

从各种数据库(包括 PubMed、MEDLINE、EMBASE、Cochrane 图书馆、Web of Science 和 Scopus)中检索到截至 2020 年 8 月的相关 907 篇文章,并查阅了参考文献列表。

结果

纳入了 4 项共 208 例患者的研究。BRP 组的呼吸暂停低通气指数(AHI)平均降低 74.03%,ESP 组的 AHI 平均降低 60.17%。BRP 组和 ESP 组的平均成功率分别为 84.96%和 79.87%。组间 AHI 变化的平均差值(MD)无显著差异(MD=-1.24 次/小时,95%CI[-11.86,9.36],P=0.82)。两组术后 AHI、术后 Epworth 嗜睡量表评分、疼痛、住院时间、开始口服饮食的时间和氧减指数变化均无显著差异,而 BRP 组的镇痛需求较低。BRP 组的手术时间较低(MD=21.72 分钟,95%CI[18.85,24.60],P<0.0001)。

结论

在治疗腭后塌陷所致 OSA 方面,两种术式的疗效相当。BRP 在手术时间方面优于 ESP。然而,需要开展多中心合作和长期随访的随机对照临床试验,以进一步证实这些术式的疗效。

喉镜,131:1420-1428,2021。

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