School of Health and Exercise Sciences, Faculty of Health and Social Development, The University of British Columbia Okanagan, ART 360 (Arts Building), 1147 Research Road, Kelowna, BC, V1V 1V7, Canada.
School of Health and Rehabilitation Sciences, The University of Queensland, St Lucia, QLD, Australia.
Exp Brain Res. 2024 Nov;242(11):2545-2556. doi: 10.1007/s00221-024-06918-4. Epub 2024 Sep 17.
Sleep deprivation alters cognitive and sensorimotor function, but its effects on the control of standing balance are inconclusive. The vestibular system is critical for standing balance, and is modified by sleep deprivation; however, how sleep deprivation affects vestibular-evoked balance responses is unknown. Thus, this study aimed to examine the effect of 24 h of sleep deprivation on the vestibular control of standing balance. During both a well-rested (i.e., control) and sleep deprivation condition, nine females completed two 90-s trials of bilateral, binaural stochastic electrical vestibular stimulation (EVS) and two 120-s trials of quiet stance on a force plate. Quiet stance performance was assessed by center of pressure displacement parameters. Mediolateral ground reaction force (ML force) and surface electromyography (EMG) of the right medial gastrocnemius (MG) were sampled simultaneously with the EVS signal to quantify vestibular control of balance within the frequency (gain and coherence) and time (cumulant density) domains. Twenty-four hours of sleep deprivation did not affect quiet stance performance. Sleep deprivation also had limited effect on EVS-MG EMG and EVS-ML Force coherence (less than control at 8-10.5 Hz, greater at ~ 16 Hz); however, gain of EVS-MG EMG (< 8, 11-24 Hz) and EVS-ML force (0.5-9 Hz) was greater for sleep deprivation than control. Sleep deprivation did not alter peak-to-peak amplitude of EVS-MG EMG (p = 0.51) or EVS-ML force (p = 0.06) cumulant density function responses. Despite no effect on quiet stance parameters, the observed increase in vestibular-evoked balance response gain suggests 24-h sleep deprivation may lead to greater sensitivity of the central nervous system when transforming vestibular-driven signals for standing balance control.
睡眠剥夺会改变认知和感觉运动功能，但它对站立平衡控制的影响尚无定论。前庭系统对站立平衡至关重要，并且会受到睡眠剥夺的影响；然而，睡眠剥夺如何影响前庭诱发的平衡反应尚不清楚。因此，本研究旨在探讨 24 小时睡眠剥夺对站立平衡前庭控制的影响。在休息良好（即对照）和睡眠剥夺条件下，9 名女性完成了两次双侧、双耳随机电前庭刺激（EVS）90 秒试验和两次 120 秒安静站立试验，试验在力板上进行。安静站立的性能通过中心压力位移参数进行评估。在 EVS 信号的同时采集右侧内侧腓肠肌（MG）的中侧地面反作用力（ML 力）和表面肌电图（EMG），以在频率（增益和相干性）和时间（累积密度）域内量化平衡的前庭控制。24 小时的睡眠剥夺并未影响安静站立的表现。睡眠剥夺对 EVS-MG EMG 和 EVS-ML 力相干性的影响也有限（8-10.5Hz 时小于对照，16Hz 时大于对照）；然而，EVS-MG EMG（<8、11-24Hz）和 EVS-ML 力（0.5-9Hz）的 EVS 增益在睡眠剥夺时大于对照。EVS-MG EMG（p=0.51）或 EVS-ML 力（p=0.06）累积密度函数反应的 EVS-MG EMG 的峰峰值幅度在睡眠剥夺时没有变化。尽管对安静站立参数没有影响，但观察到的前庭诱发平衡反应增益增加表明，24 小时睡眠剥夺可能导致中枢神经系统在转换前庭驱动信号以控制站立平衡时更敏感。
