Wijlens Kim A E, Witteveen Annemieke, Beenhakker Lian, Siemerink Ester J M, Achterkamp Reinoud, Siesling Sabine, Vollenbroek-Hutten Miriam M R, Bode Christina
Department of Biomedical Signals and Systems, Technical Medical Centre, University of Twente, Enschede, The Netherlands.
Department of Internal Medicine, ZiekenhuisGroep Twente, Hengelo, The Netherlands.
Fatigue. 2024 Aug 18;12(4):293-307. doi: 10.1080/21641846.2024.2389007. eCollection 2024.
Cancer-related fatigue (CRF) affects the quality of life after breast cancer. In a previous study, we developed a 72-item questionnaire that assesses CRF from a holistic point of view; named the Holistic Assessment of CRF (HA-CRF) questionnaire. The current study assessed the face and content validity of the HA-CRF questionnaire.
Using a mixed-method approach, ten breast cancer survivors (BCS) did a cognitive walkthrough of the HA-CRF via an app followed by a semi-structured interview about relevancy and essentiality (qualitative). In addition, ten health care professionals (HCPs) assessed the relevancy, clarity, and essentiality of each item via a questionnaire (quantitative).
BCS indicated minor textual improvement for four items and six items were not completely clear. The app was considered easy to use and the HC-CRF was on average completed in 18 minutes. The HA-CRF questionnaire provided openness about fatigue and gave the feeling of being heard. The items were helpful and induced self-awareness. HCPs indicated 71% of items being very clear or minor revisions proposed by the minority, with 64% of items being essential and 92% considered relevant.
The HA-CRF showed good face and excellent content validity. Further research is needed to assess its ability to monitor in daily life.
癌症相关疲劳（CRF）会影响乳腺癌患者的生活质量。在之前的一项研究中，我们编制了一份包含72个条目的问卷，从整体角度评估CRF，即癌症相关疲劳整体评估（HA-CRF）问卷。本研究评估了HA-CRF问卷的表面效度和内容效度。
采用混合方法，十名乳腺癌幸存者（BCS）通过一款应用程序对HA-CRF进行认知预演，随后进行关于相关性和必要性的半结构化访谈（定性研究）。此外，十名医疗保健专业人员（HCP）通过问卷评估每个条目的相关性、清晰度和必要性（定量研究）。
乳腺癌幸存者指出四个条目在文字上需稍作改进，六个条目不完全清晰。该应用程序被认为易于使用，HA-CRF问卷平均完成时间为18分钟。HA-CRF问卷为疲劳问题提供了开放性，让人有被倾听的感觉。这些条目很有帮助，能引发自我意识。医疗保健专业人员指出，71%的条目非常清晰或少数人提出了轻微修改建议，64%的条目至关重要，92%的条目被认为相关。
HA-CRF显示出良好的表面效度和出色的内容效度。需要进一步研究以评估其在日常生活中的监测能力。
