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用于食品和饲料生产的单细胞蛋白（SCP）技术的最新进展与挑战

Recent advances and challenges in single cell protein (SCP) technologies for food and feed production.

作者信息

Li Yu Pin, Ahmadi Fatemeh, Kariman Khalil, Lackner Maximilian

机构信息

College of Agricultural Resources and Environmental Science, Yunnan Agricultural University, Kunming, 650201, China.

School of Agriculture and Environment, University of Western Australia, Crawley, WA, 6009, Australia.

出版信息

NPJ Sci Food. 2024 Sep 18;8(1):66. doi: 10.1038/s41538-024-00299-2.

DOI:10.1038/s41538-024-00299-2
PMID:39294139
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11410949/
Abstract

The global population is increasing, with a predicted demand for 1250 million tonnes of animal-derived protein by 2050, which will be difficult to meet. Single-cell protein (SCP) offers a sustainable solution. This review covers SCP production mechanisms, microbial and substrate choices, and advancements in metabolic engineering and CRISPR-Cas. It emphasizes second-generation substrates and fermentation for a circular economy. Despite challenges like high nucleic acid content, SCP promises to solve the global nutrition problem.

摘要

全球人口正在增长，预计到2050年对12.5亿吨动物源蛋白质的需求将难以满足。单细胞蛋白（SCP）提供了一种可持续的解决方案。本综述涵盖了SCP的生产机制、微生物和底物选择以及代谢工程和CRISPR-Cas的进展。它强调了用于循环经济的第二代底物和发酵。尽管存在核酸含量高等挑战，但SCP有望解决全球营养问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/44d07ae1597f/41538_2024_299_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/9c83651e0aac/41538_2024_299_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/7b380b8a4cc4/41538_2024_299_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/78c720a76514/41538_2024_299_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/77894b006f14/41538_2024_299_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/ddd6cb569c67/41538_2024_299_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/9e937376803f/41538_2024_299_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/3f54da14c0e8/41538_2024_299_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/0e7d40748e09/41538_2024_299_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/44d07ae1597f/41538_2024_299_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/9c83651e0aac/41538_2024_299_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/7b380b8a4cc4/41538_2024_299_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/78c720a76514/41538_2024_299_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/77894b006f14/41538_2024_299_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/ddd6cb569c67/41538_2024_299_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/9e937376803f/41538_2024_299_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/3f54da14c0e8/41538_2024_299_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/0e7d40748e09/41538_2024_299_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4a/11410949/44d07ae1597f/41538_2024_299_Fig9_HTML.jpg

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