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基于残疾调整生命年指数的撒哈拉以南非洲国家缺血性脑卒中负担 - 趋势分析和危险因素识别。

Burden of ischemic stroke in sub-Saharan African countries based on DALYs index - trend analysis and identification of risk factors.

机构信息

Zakład Zdrowia Publicznego, Warszawski Uniwersytet Medyczny, Polska.

Oddział Wewnętrzny, Szpital Powiatowy im. dra Tytusa Chałubińskiego w Zakopanem, Polska.

出版信息

Przegl Epidemiol. 2024 Sep 18;78(2):193-206. doi: 10.32394/pe/190845. Epub 2024 Jul 9.

DOI:10.32394/pe/190845
PMID:39295186
Abstract

BACKGROUND

Stroke burden, measured by DALYs, reveals a growing concern in sub-Saharan Africa. Ischemic stroke, exacerbated by modifiable risk factors like hypertension and household air pollution, poses a significant health challenge. Regional disparities, economic development, and healthcare inefficiencies underscore the need for targeted interventions and further research.

OBJECTIVE

This study aims to analyze trends in the burden of ischemic stroke across specific regions in sub-Saharan Africa from 2000 to 2019. The objective is to identify key changes in stroke burden progression and highlight modifiable risk factors.

MATERIAL AND METHODS

Utilizing World Health Organization (WHO) data from 2000 and 2019, national estimates of ischemic stroke DALYs in 49 sub-Saharan African countries were collected. DALYs were calculated per 100,000 population to reduce the impact of population size. Statistical analyses and visual representations using MapChart were employed to interpret the trends.

RESULTS

The study reveals wide variations in ischemic stroke DALYs changes across sub-Saharan African countries from 2000 to 2019. Predominantly, countries in the Eastern and Southern regions experienced adverse increases, while those in the Central and West regions mostly exhibited declines in DALYs. Countries such as Lesotho, Zimbabwe, and Mauritius, saw the most significant DALYs increases, whereas Rwanda, Malawi, and Equatorial Guinea experienced the most favorable changes.

CONCLUSIONS

Stroke is a pressing health concern in sub-Saharan Africa. Modifiable risk factors like hypertension and household air pollution necessitate targeted interventions. Tailored healthcare policies, reinforced health systems and comprehensive research into region-specific risk factors are crucial to alleviate stroke-related morbidity and mortality in the region. Addressing these challenges is vital to mitigate the increasing burden of stroke in the particular regions of sub-Saharan Africa.

摘要

背景

以残疾调整生命年(DALYs)衡量的卒中负担在撒哈拉以南非洲日益受到关注。高血压和家庭空气污染等可改变的风险因素使缺血性卒中更为恶化,对健康构成重大挑战。区域差异、经济发展和医疗保健效率低下突显了有针对性的干预措施和进一步研究的必要性。

目的

本研究旨在分析 2000 年至 2019 年期间撒哈拉以南非洲特定地区缺血性卒中负担的趋势。目的是确定卒中负担变化的关键,并强调可改变的风险因素。

材料和方法

利用世界卫生组织(WHO)2000 年和 2019 年的数据,收集了撒哈拉以南非洲 49 个国家缺血性卒中 DALYs 的国家估计值。DALYs 按每 10 万人计算,以降低人口规模的影响。使用 MapChart 进行统计分析和可视化表示,以解释趋势。

结果

研究显示,2000 年至 2019 年期间,撒哈拉以南非洲国家缺血性卒中 DALYs 变化存在广泛差异。主要是东部和南部地区的国家经历了不利的增加,而中部和西部地区的国家则大多出现 DALYs 的下降。莱索托、津巴布韦和毛里求斯等国家的 DALYs 增加最为显著,而卢旺达、马拉维和赤道几内亚的变化最为有利。

结论

卒中是撒哈拉以南非洲地区的一个紧迫的健康问题。高血压和家庭空气污染等可改变的风险因素需要有针对性的干预措施。制定针对特定区域风险因素的医疗保健政策、加强卫生系统和全面研究至关重要,以减轻该地区与卒中相关的发病率和死亡率。应对这些挑战对于减轻撒哈拉以南非洲特定地区卒中负担的增加至关重要。

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