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妊娠期溶血、肝酶升高、血小板减少综合征(HELLP)与子痫前期标准的不一致性:对医学教育和产科培训的启示

Incongruence of Hemolysis, Elevated Liver Enzyme, Low-Platelet Count Syndrome (HELLP) and Preeclampsia Criteria in Pregnancy: Implications for Medical Education and Obstetrics Training.

作者信息

Jenkins Jacob, Ferozuddin Aleena A, Mourad Jad, Abdulla Zayna Z, Oviedo Angelica

机构信息

Physiology & Pathology, Burrell College of Osteopathic Medicine, Las Cruces, USA.

Pathology and Laboratory Medicine, Burrell College of Osteopathic Medicine, Melbourne, USA.

出版信息

Cureus. 2024 Aug 19;16(8):e67211. doi: 10.7759/cureus.67211. eCollection 2024 Aug.

Abstract

There is conflicting information in the medical literature regarding hemolysis, elevated liver enzymes, low platelet count syndrome (HELLP) and preeclampsia and whether they are subsets of a single disease or distinct complications of pregnancy. In numerous places, HELLP is described as a severe form or later stage of preeclampsia. However, a detailed medical literature search utilizing NCBI, PubMed, and Elicit: The AI Research Assistant clearly demonstrates that HELLP and preeclampsia are distinct diseases. While they share similarities, each one has unique diagnostic criteria, pathophysiology, and treatment. We believe that these entities should be taught as separate entities to medical students and residents because this will result in better patient care. Medical educational theories, including constructivism, demonstrate that initial learning experiences heavily influence future learning. The joining of HELLP and preeclampsia in medical school teaching materials is detrimental to students' and trainees' long-term understanding of these two serious complications of pregnancy.

摘要

医学文献中关于溶血、肝酶升高、血小板减少综合征(HELLP)和子痫前期以及它们是单一疾病的亚型还是妊娠的不同并发症存在相互矛盾的信息。在许多地方,HELLP被描述为子痫前期的严重形式或晚期阶段。然而,利用美国国立医学图书馆(NCBI)、医学期刊数据库(PubMed)和人工智能研究助手Elicit进行的详细医学文献检索清楚地表明,HELLP和子痫前期是不同的疾病。虽然它们有相似之处,但每种疾病都有独特的诊断标准、病理生理学和治疗方法。我们认为,应该将这些疾病作为独立的实体向医学生和住院医生传授,因为这将带来更好的患者护理。包括建构主义在内的医学教育理论表明,最初的学习经历会严重影响未来的学习。在医学院教材中将HELLP和子痫前期合并在一起不利于学生和实习生对这两种严重妊娠并发症的长期理解。

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本文引用的文献

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HELLP Syndrome.HELLP 综合征。
Crit Care Nurs Clin North Am. 2022 Sep;34(3):277-288. doi: 10.1016/j.cnc.2022.04.009. Epub 2022 Jul 20.

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