Guo Pan, Tao Fang, Ma Chunpeng, Bi Xile, Zhu Aihong, Wang Wenguang, Yang Hongmei
Department of Cardiology, Qinhuangdao First Hospital, Qinhuangdao, Hebei Province, 066000, China.
Medical Department, Qinhuangdao First Hospital, Qinhuangdao, Hebei Province, 066000, China.
Heliyon. 2024 Aug 30;10(17):e37139. doi: 10.1016/j.heliyon.2024.e37139. eCollection 2024 Sep 15.
In recent years, numerous studies have suggested that the gut microbiota and its metabolites are closely related to myocardial infarction. Utilizing insights from these research findings may be advantageous in the prevention, treatment, and prognosis of myocardial infarction. We have employed bibliometric methodology to summarize the progress made in this research area over the past 20 years, identify the hotspots, and highlight the developmental tendencies, providing a reference for future research in this field.
We searched the content related to this field in the Web of Science Core Collection database, with a time range from 2001 to 2023. We used VOSviewer, CiteSpace, and Scimago Graphica software to visualize the search results.
We included 889 reports in this study. The country with the most publications was China, while the country with the greatest influence was the United States. An analysis of institutions showed that the Chinese Academy of Medical Sciences had the largest volume of publications, whereas the Cleveland Clinic had the most influential ones. An author analysis showed Stanley L Hazen to have published the most and to also have been the most influential researcher. An analysis of all the journals publishing articles related to the search terms showed that PLoS One journal had the highest number of publications (18 articles), while Atherosclerosis journal had the most influential articles. The results of our reference analysis showed a strong association between Trimethylamine N-oxide and myocardial infarction. We found that increased intestinal permeability may be related to the progression of cardiovascular diseases, a high-fiber diet may help in the prevention of diseases such as myocardial infarction, and populations with a high intake of red meat may have an increased risk of myocardial infarction. Keyword analysis suggested that 'cardiac fibrosis' and 'major bleeding' were promising research directions in the future, and supplementing food intake with short-chain fatty acids was looked upon as a promising approach to treating coronary heart disease.
The gut microbiota are closely related to myocardial infarction, and investigating this relationship is crucial for the prevention and treatment of myocardial infarction, where interdisciplinary research and international cooperation are indispensable.
近年来，大量研究表明肠道微生物群及其代谢产物与心肌梗死密切相关。利用这些研究结果的见解可能有利于心肌梗死的预防、治疗和预后。我们采用文献计量学方法总结了过去20年该研究领域取得的进展，确定了热点，并突出了发展趋势，为该领域未来的研究提供参考。
我们在科学网核心合集数据库中搜索了与该领域相关的内容，时间范围为2001年至2023年。我们使用VOSviewer、CiteSpace和Scimago Graphica软件对搜索结果进行可视化。
本研究纳入了889篇报告。发表论文最多的国家是中国，而最具影响力的国家是美国。机构分析表明，中国医学科学院发表的论文数量最多，而克利夫兰诊所发表的论文最具影响力。作者分析表明，斯坦利·L·黑曾发表的论文最多，也是最具影响力的研究人员。对所有发表与搜索词相关文章的期刊进行分析表明，《公共科学图书馆·综合》期刊发表的文章数量最多（18篇），而《动脉粥样硬化》期刊发表的文章最具影响力。我们的参考文献分析结果表明，氧化三甲胺与心肌梗死之间存在密切关联。我们发现肠道通透性增加可能与心血管疾病的进展有关，高纤维饮食可能有助于预防心肌梗死等疾病，红肉摄入量高的人群患心肌梗死的风险可能增加。关键词分析表明，“心脏纤维化”和“大出血”是未来有前景的研究方向，补充短链脂肪酸的食物摄入被视为治疗冠心病的一种有前景的方法。
肠道微生物群与心肌梗死密切相关，研究这种关系对于心肌梗死的预防和治疗至关重要，其中跨学科研究和国际合作不可或缺。
