Hu Jiahui, Yao Qigu, Zhao Linjun
Department of Pathology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou City, 310003, China.
State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Medical Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou City, 310003, China.
Heliyon. 2024 Sep 14;10(18):e37921. doi: 10.1016/j.heliyon.2024.e37921. eCollection 2024 Sep 30.
In the last two decades, the role of the gut microbiome in the development, maintenance, and outcome of sepsis has received increased attention; however, few descriptive studies exist on its research focus, priorities, and future prospects. This study aimed to identify the current state, evolution, and emerging trends in the field of gut microbiota and sepsis using bibliometric analysis.
All publications on sepsis and gut microbiota were retrieved from the Web of Science Core Collection and included in this study. VOSviewer, CiteSpace, and the Web of Science online analysis platform were used to visualize trends based on publication country, institution, author, journal, and keywords.
A total of 1,882 articles on sepsis-related gut microbiota were screened, mainly from 95 countries or regions and 2,581 institutions. The United States and China contributed the most to this research field, with 521 (27.683 %) and 376 (19.979 %) articles, respectively. Scientists from the University of California were the most prolific, publishing 63 (3.348 %) articles. Cani PD published papers with the highest H-index, establishing himself as a leader in the field. The most publications were published in the journals "Nutrients" and "PLOS One." The journals with the most co-citations were "PLOS One," "Nature," and "Gut." The most used keywords were prebiotics, gut microbiota, and sepsis. The keyword burst research analysis revealed that research on treatment strategies based on the intestinal microbiota, intestine-liver axis, and regulatory mechanisms of bacterial metabolites are currently hot directions.
This study presents a global overview of the current state and potential trends in the field of sepsis-related gut microbiota. This study identified hot research sub-directions and new trends through comparison and analysis, which will aid in the development of this field.
在过去二十年中，肠道微生物群在脓毒症的发生、维持及预后中的作用受到了越来越多的关注；然而，关于其研究重点、优先事项和未来前景的描述性研究却很少。本研究旨在通过文献计量分析确定肠道微生物群与脓毒症领域的现状、演变及新趋势。
从科学网核心合集检索所有关于脓毒症和肠道微生物群的出版物并纳入本研究。使用VOSviewer、CiteSpace和科学网在线分析平台，根据出版国家、机构、作者、期刊和关键词来可视化趋势。
共筛选出1882篇关于脓毒症相关肠道微生物群的文章，主要来自95个国家或地区以及2581个机构。美国和中国对该研究领域的贡献最大，分别有521篇（27.683%）和376篇（19.979%）文章。加利福尼亚大学的科学家发表文章最多，共63篇（3.348%）。卡尼·P·D发表的论文H指数最高，确立了他在该领域的领先地位。发表文章最多的期刊是《营养素》和《公共科学图书馆·综合》。被共引次数最多的期刊是《公共科学图书馆·综合》《自然》和《肠道》。使用最多的关键词是益生元、肠道微生物群和脓毒症。关键词突现研究分析表明，基于肠道微生物群的治疗策略、肠-肝轴以及细菌代谢产物的调节机制的研究是当前的热点方向。
本研究对脓毒症相关肠道微生物群领域的现状和潜在趋势进行了全球概述。本研究通过比较和分析确定了热门研究子方向和新趋势，这将有助于该领域的发展。
