Ouyang Jiahui, Zhao Lingli, Song Yewen, Qu Hua, Du Tianyi, Shi Liu, Cui Zhijie, Jiang Zhonghui, Gao Zhuye
Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China.
National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Heliyon. 2024 Feb 7;10(4):e25995. doi: 10.1016/j.heliyon.2024.e25995. eCollection 2024 Feb 29.
The incidence of heart failure, the terminal stage of several cardiovascular diseases, is increasing owing to population growth and aging. Bidirectional crosstalk between the gut and heart plays a significant role in heart failure. This study aimed to analyze the gut-heart axis and heart failure from a bibliometric perspective.
We extracted literature regarding the gut-heart axis and heart failure from the Web of Science Core Collection database (January 1, 1993, to June 30, 2023) and conducted bibliometric and visualization analyses using Microsoft Excel, CiteSpace, VOSviewer, and the R package "bibliometrix."
The final analysis included 1646 articles with an average of 35.38 citations per article. Despite some fluctuations, the number of articles published per year has steadily increased over the past 31 years, particularly since 2018. A total of 9412 authors from 2287 institutions in 86 countries have contributed to this field. The USA and China have been the most productive countries, with the Cleveland Clinic in the USA and Charité-Universitätsmedizin Berlin in Germany being the most active institutions. The cooperation between countries/regions and institutions was relatively close. Professor Tang WHW was the most productive author in the field and the journal published the highest number of articles. "Heart failure," "gut microbiota," "trimethylamine N-oxide," and "inflammation" were the most common keywords, representing the current research hotspots. The keyword burst analysis indicated that "gut microbiota" and "short-chain fatty acids" are the current frontier research topics in this field.
Research on the gut-heart axis and heart failure is increasing. This bibliometric analysis indicated that the mechanisms associated with the gut-heart axis and heart failure, particularly the gut microbiota, trimethylamine N-oxide, inflammation, and short-chain fatty acids, will become hotspots and emerging trends in research in this field. These findings provide valuable insights into current research and future directions.
心力衰竭是多种心血管疾病的终末期阶段，由于人口增长和老龄化，其发病率正在上升。肠道与心脏之间的双向串扰在心力衰竭中起着重要作用。本研究旨在从文献计量学角度分析肠道-心脏轴与心力衰竭。
我们从科学网核心合集数据库（1993年1月1日至2023年6月30日）中提取了关于肠道-心脏轴与心力衰竭的文献，并使用Microsoft Excel、CiteSpace、VOSviewer和R包“bibliometrix”进行文献计量学和可视化分析。
最终分析纳入了1646篇文章，每篇文章平均被引35.38次。尽管有一些波动，但在过去31年里，每年发表的文章数量稳步增加，特别是自2018年以来。来自86个国家2287个机构的9412位作者为该领域做出了贡献。美国和中国是发文量最多的国家，美国的克利夫兰诊所和德国的柏林夏里特大学医学中心是最活跃的机构。国家/地区与机构之间的合作相对紧密。唐WHW教授是该领域发文量最多的作者，该期刊发表的文章数量最多。“心力衰竭”“肠道微生物群”“氧化三甲胺”和“炎症”是最常见的关键词，代表了当前的研究热点。关键词突现分析表明，“肠道微生物群”和“短链脂肪酸”是该领域当前的前沿研究主题。
关于肠道-心脏轴与心力衰竭的研究正在增加。这项文献计量学分析表明，与肠道-心脏轴和心力衰竭相关的机制，特别是肠道微生物群、氧化三甲胺、炎症和短链脂肪酸，将成为该领域研究的热点和新趋势。这些发现为当前的研究和未来方向提供了有价值的见解。
