Zhang Bin, Zhang Zhaofang, Huang Xin, Ren Weilian, Wang Junxia
Department of Anesthesiology, Children's Hospital Affiliated to Shandong University (Jinan Children's Hospital), Jinan, Shandong Province, PR China; School of Pharmacy, Linyi University, Linyi, Shandong Province, PR China.
Department of Nursing, Children's Hospital Affiliated to Shandong University (Jinan Children's Hospital), Jinan, Shandong Province, PR China.
J Perianesth Nurs. 2025 Apr;40(2):349-355. doi: 10.1016/j.jopan.2024.05.012. Epub 2024 Sep 19.
The present study aimed to evaluate the effects of three different doses of ropivacaine in Shang Ring circumcision in school-aged children.
This is a prospective, randomized, controlled study.
A total of 148 American Society of Anesthesiologists I to II children were enrolled and randomly assigned into the R0.2%, R0.25%, and R0.3% groups. These groups received 0.2%, 0.25%, and 0.3% of ropivacaine (0.5 mL/kg) for caudal block, respectively. The perioperative data on anesthesia quality (including adequate analgesia rate, analgesic duration, lower extremity numbness duration, and postoperative first urination time), and adverse events were collected. Hemodynamic variables were also measured perioperatively.
The adequate analgesia rate of caudal block in the R0.2% group (75.5%) was significantly lower than that in the R0.25% (94.0%) and R0.3% groups (98.0%) (P = .001). The analgesic duration of the R0.2% and R0.25% groups was significantly less than that of the R0.3% group (P < .001). The duration of lower extremity numbness in R0.2% group was significantly shorter than that in R0.25% (P < .05) and R0.3% groups (P < .01), and there was no significant difference between the R0.25% and R0.3% groups. The first urination time of R0.2% was significantly shorter than the R0.3% group (P < .05). There was no significant difference between the R0.2% and R0.25% or the R0.25% and R0.3% groups. No significant difference was found in adverse effects among groups (P > .05).
Caudal block with 0.3% ropivacaine can provide more satisfactory intraoperative analgesia quality for school-aged children receiving Shang Ring circumcision, without increasing the risk of adverse effects.
本研究旨在评估三种不同剂量的罗哌卡因在学龄儿童上环包皮环切术中的效果。
这是一项前瞻性、随机、对照研究。
共纳入148例美国麻醉医师协会I至II级的儿童，并随机分为0.2%罗哌卡因组、0.25%罗哌卡因组和0.3%罗哌卡因组。这些组分别接受0.2%、0.25%和0.3%的罗哌卡因（0.5 mL/kg）用于骶管阻滞。收集围手术期麻醉质量（包括充分镇痛率、镇痛持续时间、下肢麻木持续时间和术后首次排尿时间）及不良事件的数据。围手术期还测量血流动力学变量。
0.2%罗哌卡因组骶管阻滞的充分镇痛率（75.5%）显著低于0.25%罗哌卡因组（94.0%）和0.3%罗哌卡因组（98.0%）（P = 0.001）。0.2%罗哌卡因组和0.25%罗哌卡因组的镇痛持续时间显著短于0.3%罗哌卡因组（P < 0.001）。0.2%罗哌卡因组下肢麻木持续时间显著短于0.25%罗哌卡因组（P < 0.05）和0.3%罗哌卡因组（P < 0.01），0.25%罗哌卡因组和0.3%罗哌卡因组之间无显著差异。0.2%罗哌卡因组的首次排尿时间显著短于0.3%罗哌卡因组（P < 0.05）。0.2%罗哌卡因组与0.25%罗哌卡因组或0.25%罗哌卡因组与0.3%罗哌卡因组之间无显著差异。各组间不良反应无显著差异（P > 0.05）。
0.3%罗哌卡因骶管阻滞可为接受上环包皮环切术的学龄儿童提供更满意的术中镇痛质量，且不增加不良反应风险。
