关于γ-氨基丁酸能对人体运动诱导的生长激素升高的控制的证据。
Evidence for a GABAergic control of the exercise-induced rise in GH in man.
作者信息
Steardo L, Iovino M, Monteleone P, Agrusta M, Orio F
出版信息
Eur J Clin Pharmacol. 1985;28(5):607-9. doi: 10.1007/BF00544075.
PMID:3930260
Abstract
The effect of the GABAergic drug sodium valproate (SV) on the exercise-induced release of growth hormone (GH) was investigated in 10 healthy males. The exercise test consisted of using a stationary bicycle ergometer at 450 kg/min for 20 min. SV 600 mg blunted the increase in GH induced by the exercise, suggesting GABAergic regulation of GH secretion in man, at least under certain physiological conditions.
摘要
在10名健康男性中研究了γ-氨基丁酸能药物丙戊酸钠（SV）对运动诱导的生长激素（GH）释放的影响。运动测试包括使用固定自行车测力计，以450千克/分钟的速度骑行20分钟。600毫克的SV减弱了运动诱导的GH增加，这表明至少在某些生理条件下，γ-氨基丁酸能对人体GH分泌有调节作用。
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