Sudo A
Eur J Pharmacol. 1985 Aug 7;114(1):79-83. doi: 10.1016/0014-2999(85)90524-2.
To examine the location of adrenaline in peripheral organs of mammals, adrenaline and noradrenaline were measured in several organs of rats treated with 6-hydroxydopamine (6-OHDA) or vehicle. After the administration of 6-OHDA, there was a marked decrease in the content of both adrenaline and noradrenaline in the heart, spleen, submaxillary gland of the rat. This finding suggests that in rats adrenaline is present in noradrenaline neurons in these organs.
为了研究肾上腺素在哺乳动物外周器官中的定位，对用6-羟基多巴胺（6-OHDA）或赋形剂处理的大鼠的多个器官中的肾上腺素和去甲肾上腺素进行了测量。给予6-OHDA后，大鼠心脏、脾脏、颌下腺中的肾上腺素和去甲肾上腺素含量均显著降低。这一发现表明，在大鼠中，这些器官的去甲肾上腺素能神经元中存在肾上腺素。
