• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

社会经济劣势在整个发展过程中出现的时间对抑郁症状和大脑结构的重要性。

The importance of timing of socioeconomic disadvantage throughout development for depressive symptoms and brain structure.

机构信息

PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.

Center for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo, Norway.

出版信息

Dev Cogn Neurosci. 2024 Oct;69:101449. doi: 10.1016/j.dcn.2024.101449. Epub 2024 Sep 13.

DOI:10.1016/j.dcn.2024.101449
PMID:39303431
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11439534/
Abstract

Prior studies have reported associations between socioeconomic disadvantage, brain structure and mental health outcomes, but the timing of these relations is not well understood. Using prospective longitudinal data from the Avon Longitudinal Study of Parents and Children (ALSPAC), this preregistered study examined whether socioeconomic disadvantage related differentially to depressive symptoms (n=3012-3530) and cortical and subcortical structures (n=460-733) in emerging adults, depending on the timing of exposure to socioeconomic disadvantage. Family income in early childhood and own income measured concurrently were both significantly related to depressive symptoms in emerging adulthood. Similar results were observed for perceived financial strain. In contrast, only family income in early childhood was associated with brain structure in emerging adulthood, with positive associations with intracranial volume and total and regional cortical surface area. The findings suggest that both objective and subjective aspects of one's financial standing throughout development relate to depressive symptoms in adulthood, but that specifically early life family income is related to brain structural features in emerging adulthood. This suggests that associations between socioeconomic disadvantage and brain structure originate early in neurodevelopment, highlighting the role of timing of socioeconomic disadvantage.

摘要

先前的研究报告了社会经济劣势、大脑结构和心理健康结果之间的关联，但这些关系的时间顺序尚不清楚。本预注册研究使用了来自阿冯纵向父母与子女研究（ALSPAC）的前瞻性纵向数据，检验了社会经济劣势是否根据社会经济劣势暴露的时间不同，对成年早期的抑郁症状（n=3012-3530）和皮质和皮质下结构（n=460-733）产生不同的影响。儿童早期的家庭收入和同期测量的个人收入都与成年早期的抑郁症状显著相关。对经济压力的感知也出现了类似的结果。相比之下，只有儿童早期的家庭收入与成年早期的大脑结构相关，与颅内体积、总皮质表面积和区域皮质表面积呈正相关。研究结果表明，一个人在整个发展过程中经济状况的客观和主观方面都与成年后的抑郁症状有关，但具体来说，儿童早期的家庭收入与成年早期的大脑结构特征有关。这表明社会经济劣势与大脑结构之间的关联起源于神经发育的早期，突出了社会经济劣势时间的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/b9fb6ec00e68/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/b9a8b91f7c90/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/6fd36de4c925/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/9f2ae52f3ccb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/59f52ca18e2b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/c0b3f99ccfb1/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/b9fb6ec00e68/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/b9a8b91f7c90/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/6fd36de4c925/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/9f2ae52f3ccb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/59f52ca18e2b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/c0b3f99ccfb1/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f4/11439534/b9fb6ec00e68/gr6.jpg

相似文献

1
The importance of timing of socioeconomic disadvantage throughout development for depressive symptoms and brain structure.社会经济劣势在整个发展过程中出现的时间对抑郁症状和大脑结构的重要性。
Dev Cogn Neurosci. 2024 Oct;69:101449. doi: 10.1016/j.dcn.2024.101449. Epub 2024 Sep 13.
2
The Contribution of Neighborhood Socioeconomic Disadvantage to Depressive Symptoms Over the Course of Adult Life: A 32-Year Prospective Cohort Study.邻里社会经济劣势对成年后抑郁症状的影响：一项 32 年的前瞻性队列研究。
Am J Epidemiol. 2020 Jul 1;189(7):679-689. doi: 10.1093/aje/kwaa026.
3
Father absence and timing of menarche in adolescent girls from a UK cohort: the mediating role of maternal depression and major financial problems.父亲缺失与英国队列青少年初潮时间：母亲抑郁和重大财务问题的中介作用。
J Adolesc. 2014 Apr;37(3):291-301. doi: 10.1016/j.adolescence.2014.02.003. Epub 2014 Feb 22.
4
Childhood socio-economic disadvantage predicts reduced myelin growth across adolescence and young adulthood.童年时期的社会经济劣势预示着整个青春期和成年早期的髓鞘生长减少。
Hum Brain Mapp. 2020 Aug 15;41(12):3392-3402. doi: 10.1002/hbm.25024. Epub 2020 May 20.
5
Testing lifecourse theories characterising associations between maternal depression and offspring depression in emerging adulthood: the Avon Longitudinal Study of Parents and Children.检测生命历程理论，该理论描述了母亲抑郁与成年早期后代抑郁之间的关系：雅芳纵向父母与子女研究。
J Child Psychol Psychiatry. 2023 Aug;64(8):1149-1158. doi: 10.1111/jcpp.13699. Epub 2022 Sep 12.
6
Role of Positive Parenting in the Association Between Neighborhood Social Disadvantage and Brain Development Across Adolescence.积极育儿在邻里社会劣势与青少年大脑发育关联中的作用。
JAMA Psychiatry. 2017 Aug 1;74(8):824-832. doi: 10.1001/jamapsychiatry.2017.1558.
7
Influences of childhood family factors on depressive symptoms in adolescence and early adulthood: A Danish longitudinal study.童年家庭因素对青少年和成年早期抑郁症状的影响：一项丹麦纵向研究。
Scand J Public Health. 2020 Nov;48(7):715-725. doi: 10.1177/1403494819870056. Epub 2020 Jan 21.
8
Early Life Disadvantage and the Risk of Depressive Symptoms among Young Black Women.早年生活劣势与年轻黑人女性抑郁症状风险之间的关系。
J Racial Ethn Health Disparities. 2024 Jun;11(3):1819-1828. doi: 10.1007/s40615-023-01654-x. Epub 2023 Jun 28.
9
Neighbourhood disadvantage and depressive symptoms among adolescents followed into emerging adulthood.青少年期到成年早期的邻里劣势与抑郁症状。
J Epidemiol Community Health. 2019 Jul;73(7):590-597. doi: 10.1136/jech-2018-212004. Epub 2019 Mar 30.
10
Assessment of Parent Income and Education, Neighborhood Disadvantage, and Child Brain Structure.评估父母收入和教育水平、邻里劣势与儿童大脑结构。
JAMA Netw Open. 2022 Aug 1;5(8):e2226208. doi: 10.1001/jamanetworkopen.2022.26208.

引用本文的文献

1
Socioeconomic factors, brain-derived neurotrophic factor Val66Met polymorphism, and cortical structure in children and adolescents.社会经济因素、脑源性神经营养因子Val66Met多态性与儿童及青少年的皮质结构
Sci Rep. 2025 May 29;15(1):18953. doi: 10.1038/s41598-025-04081-6.
2
A developmental neuroscience perspective on youth contributions and challenges in a changing society.从发展神经科学角度看不断变化的社会中青年的贡献与挑战。
Dev Cogn Neurosci. 2025 Jun;73:101558. doi: 10.1016/j.dcn.2025.101558. Epub 2025 Apr 9.
3
The Relationship Between Mental Health Literacy and Social Well-Being: A Longitudinal Study in China.

本文引用的文献

1
Parental education and income are linked to offspring cortical brain structure and psychopathology at 9-11 years.父母的教育程度和收入与9至11岁后代的大脑皮质结构及精神病理学有关。
JCPP Adv. 2024 Feb 6;4(1):e12220. doi: 10.1002/jcv2.12220. eCollection 2024 Mar.
2
Economic hardship and adolescent behavioral outcomes: Within- and between-family associations.经济困难与青少年行为结果：家庭内部及家庭之间的关联
Dev Psychopathol. 2025 Feb;37(1):107-124. doi: 10.1017/S0954579423001451. Epub 2024 Jan 5.
3
Socioeconomic inequalities in physical, psychological, and cognitive multimorbidity in middle-aged and older adults in 33 countries: a cross-sectional study.
心理健康素养与社会福祉之间的关系：一项中国的纵向研究。
Behav Sci (Basel). 2024 Dec 30;15(1):29. doi: 10.3390/bs15010029.
4
Associations between parental psychopathology and youth functional emotion regulation brain networks.父母心理病理学与青少年功能性情绪调节脑网络的关联。
Dev Cogn Neurosci. 2024 Dec;70:101476. doi: 10.1016/j.dcn.2024.101476. Epub 2024 Nov 12.
33 个国家中年和老年人在身体、心理和认知多重疾病方面的社会经济不平等：一项横断面研究。
Lancet Healthy Longev. 2023 Nov;4(11):e618-e628. doi: 10.1016/S2666-7568(23)00195-2.
4
Financial strain and depression in the U.S.: a scoping review.美国的经济压力与抑郁：范围综述。
Transl Psychiatry. 2023 May 13;13(1):168. doi: 10.1038/s41398-023-02460-z.
5
Poverty from fetal life onward and child brain morphology.从胎儿期开始的贫困与儿童大脑形态。
Sci Rep. 2023 Jan 23;13(1):1295. doi: 10.1038/s41598-023-28120-2.
6
Associations between Socioeconomic Status, Cognition, and Brain Structure: Evaluating Potential Causal Pathways Through Mechanistic Models of Development.社会经济地位、认知与脑结构之间的关联：通过发展机制模型评估潜在因果路径。
Cogn Sci. 2023 Jan;47(1):e13217. doi: 10.1111/cogs.13217.
7
The relationship between perceived income inequality, adverse mental health and interpersonal difficulties in UK adolescents.英国青少年感知到的收入不平等、不良心理健康和人际困难之间的关系。
J Child Psychol Psychiatry. 2023 Mar;64(3):417-425. doi: 10.1111/jcpp.13719. Epub 2022 Nov 14.
8
Assessment of Parent Income and Education, Neighborhood Disadvantage, and Child Brain Structure.评估父母收入和教育水平、邻里劣势与儿童大脑结构。
JAMA Netw Open. 2022 Aug 1;5(8):e2226208. doi: 10.1001/jamanetworkopen.2022.26208.
9
Early life adversity shapes neural circuit function during sensitive postnatal developmental periods.早期生活逆境会在敏感的产后发育期间塑造神经回路功能。
Transl Psychiatry. 2022 Aug 1;12(1):306. doi: 10.1038/s41398-022-02092-9.
10
Timing-specific associations between income-to-needs ratio and hippocampal and amygdala volumes in middle childhood: A preliminary study.收入与需求比与儿童中期海马体和杏仁核体积的时间特异性关联：一项初步研究。
Dev Psychobiol. 2021 Nov;63(7):e22153. doi: 10.1002/dev.22153.