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银纳米颗粒功能化共价有机框架用于抑制食源性病原体及其在绿色葡萄保鲜中的应用。

Silver nanoparticle-functionalized covalent organic frameworks for the inhibition of foodborne pathogenic bacteria and their application in green grape preservation.

机构信息

College of Food Science and Technology, Northwest University, Laboratory of Nutritional and Healthy Food-Individuation Manufacturing Engineering/Research Center of Food Safety Risk Assessment and Control, Xi'an, Shaanxi 710069, China.

Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, Shaanxi University of Chinese Medicine, Xi'an 712046, China.

出版信息

Food Chem. 2025 Jan 15;463(Pt 2):141310. doi: 10.1016/j.foodchem.2024.141310. Epub 2024 Sep 16.

Abstract

Foodborne pathogens continue to pose a significant threat to human health. This study aims to enhance the antimicrobial activity of low-dose silver nanoparticles (AgNPs) against foodborne pathogens and use the enhanced AgNPs to preserve green grapes. A chemical delivery carrier for covalent organic frameworks (COFs) impregnated with AgNPs was developed. We investigated the bacteriostatic properties (minimum bacteriostatic concentration, bacteriostatic growth curve), the mechanism of action of the bacteriostatic agent, and the performance of the bacteriostatic film. The bacteriostatic preservation rate of the AgNPs@COFs composite on green grapes was evaluated. The minimum bacteriostatic concentration of the AgNPs@COFs composite was 10 μg/mL, and the bacteriostatic rate varied between 94.01 % and 98.77 %. The developed antibacterial AgNPs@COFs composite has potential applications in food packaging and preservation.

摘要

食源性病原体继续对人类健康构成重大威胁。本研究旨在增强低剂量银纳米颗粒(AgNPs)对食源性病原体的抗菌活性,并利用增强的 AgNPs 来保存绿葡萄。开发了一种用于负载银纳米颗粒的共价有机骨架(COFs)的化学输送载体。我们研究了抑菌剂的抑菌性能(最小抑菌浓度、抑菌生长曲线)、抑菌剂的作用机制以及抑菌膜的性能。评估了 AgNPs@COFs 复合材料对绿葡萄的抑菌保鲜效果。AgNPs@COFs 复合材料的最小抑菌浓度为 10μg/mL,抑菌率在 94.01%至 98.77%之间变化。所开发的抗菌 AgNPs@COFs 复合材料在食品包装和保鲜方面具有潜在的应用。

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