Department of Botany, North Orissa University, Baripada 757003, Odisha, India.
Department of Zoology, Seemanta Mahavidyalaya, Jharpokharia 757086, Odisha, India.
Molecules. 2018 Mar 14;23(3):655. doi: 10.3390/molecules23030655.
The present study demonstrates an economical and eco-friendly method for the synthesis of silver nanoparticles (AgNPs) using the wild mushroom . The synthesis of AgNPs was confirmed and the products characterized by UV-visible spectroscopy, dynamic light scattering spectroscopy and X-ray diffraction analysis. Furthermore, Fourier transform infrared spectroscopy (ATR-FTIR) analysis was performed to identify the viable biomolecules involved in the capping and active stabilization of AgNPs. Moreover, the average sizes and morphologies of AgNPs were analyzed by field emission scanning electron microscopy (FE-SEM). The potential impacts of AgNPs on food safety and control were evaluated by the antimicrobial activity of the synthesized AgNPs against common food-borne bacteria, namely, , , , and . The results of this study revealed that the synthesized AgNPs can be used to control the growth of food-borne pathogens and have potential application in the food packaging industry. Moreover, the AgNPs were evaluated for antioxidant activity (aDPPH), for biocompatibility (L-929, normal fibroblast cells), and for cytotoxic effects on human breast adenosarcoma cells (MCF-7 & MDA-MB231) to highlight their potential for use in a variety of bio-applications.
本研究展示了一种使用野生蘑菇合成银纳米粒子（AgNPs）的经济环保方法。通过紫外-可见光谱、动态光散射光谱和 X 射线衍射分析证实了 AgNPs 的合成，并对产物进行了表征。此外，还进行了傅里叶变换衰减全反射红外光谱（ATR-FTIR）分析，以确定参与 AgNPs 封端和有效稳定的生物活性分子。此外，通过场发射扫描电子显微镜（FE-SEM）分析了 AgNPs 的平均粒径和形貌。通过合成的 AgNPs 对常见食源性病原体的抗菌活性评估了 AgNPs 对食品安全和控制的潜在影响，即 、 、 、 、 。研究结果表明，合成的 AgNPs 可用于控制食源性病原体的生长，在食品包装行业具有潜在的应用前景。此外，还评估了 AgNPs 的抗氧化活性（aDPPH）、生物相容性（L-929，正常成纤维细胞）和对人乳腺腺肉瘤细胞（MCF-7 和 MDA-MB231）的细胞毒性作用，以突出其在各种生物应用中的潜在用途。
