Department of General Pediatrics, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, Turkey.
Department of Radiology, Faculty of Medicine, Bandırma Onyedi Eylül University, Bandırma, Balıkesir, Turkey.
Eur J Pediatr. 2024 Nov;183(11):4959-4967. doi: 10.1007/s00431-024-05774-2. Epub 2024 Sep 21.
Hand use varies according to which brain hemisphere is dominant. Early androgen exposure causes right hemisphere dominance. This study is aimed at comparing the testes and ovary sizes of healthy left-handed girls and boys with those of healthy right-handed children and investigating whether or not lateralization affects the gonads. The ovarian and testicular sizes of healthy left- and right-handed boys and girls who were similar in height, weight, and age were compared by ultrasonography. One hundred and eleven (111) children-including 26 left- and 26 right-handed girls and 31 left- and 28 right-handed boys-were included in this study. The mean age of left-handed girls was 77.2 ± 25.3 months, and the mean age of right-handed girls was 74.4 ± 25.2 months. Right transverse diameter (p = 0.004), right longitudinal diameter (p = 0.009), and right ovarian volume (p = 0.020) were larger in left-handed girls above 8 years of age than in left-handed girls below 8 years of age. However, these values were similar in right-handed girls above and below 8 years of age. In right-handed girls, the transverse diameter was larger in the right ovary than in the left ovary (0.014). Other ovarian values were similar. The mean age of left-handed boys was 85.2 ± 41.3 months, whereas the mean age of right-handed ones was 81 ± 41.2 months. Prepubertal and pubertal right- and left-handed boys had similar mean right and left testicular diameters and volumes (p > 0.05).
Lateralization affected gonad size in girls. In boys, gonads were not affected by lateralization. Cerebral lateralization may affect the hypothalamic-pituitary-gonadal axis in girls.
• Hand use varies according to which cerebral hemisphere is dominant. Males tend to be more left-handed than females. Brain asymmetry can affect the neuroendocrine axis.
• Ultrasonographic gonadal dimensions were examined in left-handed and right-handed children. Cerebral lateralization may affect the hypothalamic-pituitary-gonadal axis in girls.
比较健康左撇子女孩和男孩与健康右撇子儿童的睾丸和卵巢大小，并探讨偏侧性是否影响性腺。
通过超声检查比较身高、体重和年龄相似的健康左撇子和右撇子男孩和女孩的卵巢和睾丸大小。
本研究共纳入 111 名儿童，包括 26 名左撇子和 26 名右撇子女孩，31 名左撇子和 28 名右撇子男孩。左撇子女孩的平均年龄为 77.2±25.3 个月，右撇子女孩的平均年龄为 74.4±25.2 个月。8 岁以上左撇子女孩的右侧横径（p=0.004）、右侧长径（p=0.009）和右侧卵巢体积（p=0.020）大于 8 岁以下的左撇子女孩，但 8 岁以上和 8 岁以下的右撇子女孩这些值相似。在右撇子女孩中，右侧卵巢的横径大于左侧卵巢（0.014）。其他卵巢值相似。左撇子男孩的平均年龄为 85.2±41.3 个月，右撇子男孩的平均年龄为 81±41.2 个月。青春期前和青春期的左撇子和右撇子男孩的右侧和左侧睾丸直径和体积相似（p>0.05）。
偏侧性影响女孩的性腺大小。在男孩中，偏侧性不影响性腺。大脑偏侧性可能影响女孩的下丘脑-垂体-性腺轴。
• 手的使用方式根据哪个大脑半球占主导地位而有所不同。男性比女性更倾向于左撇子。大脑不对称可能影响神经内分泌轴。
• 检查了左撇子和右撇子儿童的超声性腺尺寸。大脑偏侧性可能影响女孩的下丘脑-垂体-性腺轴。
