Lu Mei-Qi, Xu Wan-Ai, Yu Huan
School of Pharmacy, Jiangxi University of Chinese Medicine Nanchang 330004, China.
Zhongguo Zhong Yao Za Zhi. 2024 Aug;49(16):4372-4386. doi: 10.19540/j.cnki.cjcmm.20240422.201.
Plantaginis Semen is a traditional Chinese medicine(TCM) commonly used in clinical practice in China, which has the effects of clearing heat, inducing diuresis for treating stranguria, draining dampness and relieving diarrhea, brightening eyes, and eliminating phlegm. Plantaginis Semen has a long history of processing. In the Han Dynasty, there were records of stir-frying, and then processing with wine, processing with salt water, processing with rice water, and other processing methods appeared. Plantaginis Semen after processing can weaken the cold nature of the drug, suitable for clinical application. Modern research has shown that the main chemical constituents of Plantaginis Semen are phenylethanol glycosides, cyclic enol ether terpenes, polysaccharides, and flavonoids, with diuretic, anti-inflammatory, hypoglycemic, hypolipidemic, antioxidant, and other pharmacological effects. This article reviewed the materia medica, medicine books, and related literature in various dynasties and analyzed the historical processing evolution, chemical constituents, and pharmacological effects of Plantaginis Semen, so as to provide a reference for the relevant research on Plantaginis Semen.
车前子是中国临床常用的一味中药，具有清热利尿通淋、利湿止泻、明目、祛痰的功效。车前子的炮制历史悠久，汉代就有炒法记载，之后又出现了酒制、盐制、米泔水制等炮制方法。炮制后的车前子能减弱药物的寒性，适合临床应用。现代研究表明，车前子的主要化学成分有苯乙醇苷类、环烯醚萜类、多糖类和黄酮类等，具有利尿、抗炎、降血糖、降血脂、抗氧化等药理作用。本文通过查阅历代本草、医药书籍及相关文献，分析了车前子的历史炮制沿革、化学成分和药理作用，以期为车前子的相关研究提供参考。
