Intelligent Tutoring Systems, Generative Artificial Intelligence (AI), and Healthcare Agents: A Proof of Concept and Dual-Layer Approach.

This study introduces a novel methodology for enhancing intelligent tutoring systems (ITS) through the integration of generative artificial intelligence (GenAI) and specialized AI agents. We present a proof of concept (PoC) demo that implements a dual-layer GenAI validation approach that utilizes multiple large language models to ensure the reliability and pedagogical integrity of the AI-generated content. The system features role-specific AI agents, a GenAI-powered scoring mechanism, and an AI mentor that provides periodic guidance. This approach demonstrates capabilities in dynamic scenario generation and real-time adaptability while addressing key challenges in AI-driven education, such as personalization, scalability, and domain-specific knowledge integration. Although exemplified here through a case study in healthcare root cause analysis, the methodology is designed for broad applicability across various fields. Our findings suggest that this approach has significant potential for advancing adaptive learning and personalized instruction while raising important considerations regarding ethical AI application in education. This work provides a foundation for further research into the efficacy and impact of GenAI-enhanced ITS on learning outcomes and instructional design across diverse educational domains.