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不同容量的关节周围神经群阻滞对股骨骨折手术中脊髓麻醉定位时疼痛及术后阿片类药物需求的影响;随机前瞻性研究。

Impact of Different Volumes of Pericapsular Nerve Group Block on Pain During Spinal Anesthesia Positioning and Postoperative Opioid Requirements in Femoral Fracture Surgeries; Randomized Prospective Study.

作者信息

Ertaş Gamze, Şenol Çakmak Hamiyet, Akdeniz Sevda, Yurtbay Alparslan, Polat Ebru, Yigit Yavuz, Sertöz Nezih, Tulgar Serkan

机构信息

Department of Anesthesiology, Samsun University Faculty of Medicine, Samsun Training and Research Hospital, Samsun, Turkiye.

Department of Orthopedic Surgery, Samsun University Faculty of Medicine, Samsun Training and Research Hospital, Samsun, Turkiye.

出版信息

J Pain Res. 2024 Sep 18;17:3075-3084. doi: 10.2147/JPR.S468863. eCollection 2024.

Abstract

INTRODUCTION

Hip fracture surgeries in patients present significant challenges, particularly in managing pain during spinal anesthesia positioning. The Pericapsular Nerve Group Block (PENG) has shown promise in addressing this issue, but the ideal volume of local anesthetic for PENG is still uncertain. In our study, we aimed to analyze the effects of administering PENG block with two different volumes on analgesic quality for patients undergoing hip fracture surgery.

METHODS

In this prospective, randomized controlled trial, the effects of administering a PENG block with 20 mL versus 30 mL of local anesthetic in patients undergoing hip fracture surgery under spinal anesthesia were compared. The primary outcome was pain during spinal anesthesia positioning, and secondary outcomes included postoperative pain scores and opioid consumption.

RESULTS

A total of 60 patients were analyzed, with 30 in each group. Critical parameters such as the time of spinal anesthesia administration and the satisfaction of the anesthesiologist showed no significant differences (p=0.918; p=0.741, respectively). NRS scores recorded before, during, and after the positioning for spinal anesthesia exhibited similar patterns (p=0.290; p=0.247; p=0.288, respectively). The cumulative opioid requirements did not exhibit a statistically significant difference at 24 hours (p = 0.098). Quadriceps weakness was significantly more in the PENG-30 group 6 hours after surgery but had recovered by the 9th hour (p= 0.004).

CONCLUSION

In patients undergoing hip fracture surgery, the effects of applying the PENG block with 20 mL or 30 mL of local anesthetic are comparable in terms of positioning for spinal anesthesia and postoperative analgesic requirements.

摘要

引言

髋部骨折患者的手术面临重大挑战,尤其是在脊髓麻醉定位期间的疼痛管理方面。关节囊周围神经组阻滞(PENG)在解决这一问题上显示出了前景,但PENG理想的局部麻醉药用量仍不确定。在我们的研究中,我们旨在分析对接受髋部骨折手术的患者使用两种不同用量的PENG阻滞对镇痛质量的影响。

方法

在这项前瞻性随机对照试验中,比较了在脊髓麻醉下接受髋部骨折手术的患者使用20 mL与30 mL局部麻醉药进行PENG阻滞的效果。主要结局是脊髓麻醉定位期间的疼痛,次要结局包括术后疼痛评分和阿片类药物消耗量。

结果

共分析了60例患者,每组30例。脊髓麻醉给药时间和麻醉医生满意度等关键参数无显著差异(分别为p = 0.918;p = 0.741)。脊髓麻醉定位前、定位期间和定位后的NRS评分呈现相似模式(分别为p = 0.290;p = 0.247;p = 0.288)。术后24小时累积阿片类药物需求量无统计学显著差异(p = 0.098)。术后6小时,PENG - 30组股四头肌无力明显更严重,但在第9小时已恢复(p = 0.004)。

结论

在接受髋部骨折手术的患者中,使用20 mL或30 mL局部麻醉药进行PENG阻滞在脊髓麻醉定位和术后镇痛需求方面效果相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/545c/11416788/0e89e0b7d4c1/JPR-17-3075-g0001.jpg

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