Lai Jengyu
International University of the Health Sciences, Rochester Clinic, PLC, Rochester, MN, USA (JL).
Am J Lifestyle Med. 2024 Apr 4;18(5):694-700. doi: 10.1177/15598276241242026. eCollection 2024 Sep-Oct.
Chronic wounds impact 4.5% of the US population, necessitating a comprehensive understanding of their types and underlying mechanisms. Diabetic foot ulcers (DFUs), prevalent in 25% of individuals with diabetes, contribute significantly to lower limb amputations. The pathophysiology involves neuropathy, peripheral arterial disease, impaired immunity, glycemic control, and mechanical stress. Lifestyle medicine emerges as a pivotal aspect of care, offering both prevention and treatment by integrating plant-predominant nutrition, physical activity, stress management, avoidance of harmful substances, restful sleep, and social connectedness. These interventions impact gene interactions, immune function, and tissue regeneration, playing a crucial role in chronic wound management. The standard of care involves a multidisciplinary approach, emphasizing infection and vascular management, pressure offloading, conducive wound healing environments, and lifestyle adjustments. As diabetes prevalence rises, a proactive integration of lifestyle interventions is crucial, offering a promising avenue to alleviate the growing healthcare burden associated with chronic wounds.
慢性伤口影响着4.5%的美国人口，因此有必要全面了解其类型和潜在机制。糖尿病足溃疡（DFU）在25%的糖尿病患者中普遍存在，是下肢截肢的重要原因。其病理生理学涉及神经病变、外周动脉疾病、免疫功能受损、血糖控制和机械应力。生活方式医学成为护理的关键方面，通过整合以植物为主的营养、体育活动、压力管理、避免有害物质、充足睡眠和社会联系来提供预防和治疗。这些干预措施影响基因相互作用、免疫功能和组织再生，在慢性伤口管理中发挥着关键作用。护理标准包括多学科方法，强调感染和血管管理、减轻压力、营造有利于伤口愈合的环境以及生活方式调整。随着糖尿病患病率的上升，积极整合生活方式干预措施至关重要，这为减轻与慢性伤口相关的日益增长的医疗负担提供了一条有前景的途径。
