Burnice Nalina Kumari Chellathurai, Ambalavanan Namasivayam, Rajesh Kumar Shanmugam, Mahendra Jaideep, Sudhakar Uma
Department of Periodontics, Meenakshi Ammal Dental College and Hospital, Meenakshi Academy of Higher Education and Research, Chennai, Tamil Nadu, India.
Nano biomedicine Lab, Centre for Global Health Research, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.
Bioinformation. 2024 Jul 31;20(7):765-770. doi: 10.6026/973206300200765. eCollection 2024.
Amla, scientifically known as and Acerola () both are Vitamin C fruits possess varied medicinal properties being used for preventive disease health management strategies. Therefore, it is of interest to explore the antioxidant, anti-inflammatory, antibacterial, and cytotoxic properties of aqueous extracts from Acerola and Amla. Hence, the anti-inflammatory activity of Acerola and amla was assessed using the bovine serum albumin denaturation assay (BSA Assay), antioxidant properties were compared using DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. Both extracts antibacterial activities were evaluated through the agar well diffusion technique against oral pathogens and Brine shrimp lethality assay for cytotoxicity. The current research sheds light on natural remedies for oxidative stress-related diseases, inflammatory conditions and bacterial infections, offering promising avenues for disease management and preventive healthcare strategies especially in the treatment of oral health diseases like periodontitis.
余甘子，科学名称为[此处原文缺失余甘子学名]，以及针叶樱桃（[此处原文缺失针叶樱桃学名]）均为富含维生素C的水果，具有多种药用特性，可用于疾病预防的健康管理策略。因此，探索针叶樱桃和余甘子水提取物的抗氧化、抗炎、抗菌和细胞毒性特性具有重要意义。因此，采用牛血清白蛋白变性试验（BSA试验）评估针叶樱桃和余甘子的抗炎活性，使用DPPH（2,2-二苯基-1-苦基肼）试验比较抗氧化特性。通过琼脂孔扩散技术评估两种提取物对口腔病原体的抗菌活性，并采用卤虫致死试验评估细胞毒性。目前的研究为氧化应激相关疾病、炎症和细菌感染的天然疗法提供了启示，为疾病管理和预防性医疗保健策略提供了有前景的途径，特别是在治疗牙周炎等口腔健康疾病方面。
