Straub Josina, Szymski Dominik, Walter Nike, Wu Yinan, Melsheimer Oliver, Grimberg Alexander, Alt Volker, Steinbrück Arnd, Rupp Markus
Klinik und Poliklinik für Unfallchirurgie, Universitätsklinikum Regensburg, Franz-Josef-Strauss Allee 11, 93053, Regensburg, Deutschland.
Deutsches Endoprothesenregister gGmbH (EPRD), Berlin, Deutschland.
Orthopadie (Heidelb). 2024 Oct;53(10):789-798. doi: 10.1007/s00132-024-04561-z. Epub 2024 Sep 23.
Owing to the ageing population the implantation rate of total knee arthroplasty (TKA) continues to rise. Aseptic revisions in primary TKA are one of the main causes of revision. The aim of the following study was to determine the incidence of and reasons for aseptic revision in constrained and unconstrained TKA and in unicondylar knee arthroplasty (UKA).
The data collection was carried out with the help of the German Arthroplasty Register (EPRD). The reasons for aseptic revision surgery were worked out using this. The incidence and the comparison of aseptic revisions were analysed with the aid of Kaplan-Meier estimates. A multiple Chi-squared test with the Holm method was used to identify group differences in collateral ligament deficiencies.
In total, 300,998 cases of knee arthroplasties were analysed, of which 254,144 (84.4%) were unconstrained TKA, 9993 (3.3%) were constrained TKA and 36,861 (12.3%) were UKA. The rate of aseptic revisions was significantly increased compared with unconstrained and constrained TKA (p < 0.0001). In constrained TKA, a revision rate of 2.0% for aseptic reasons was reported, whereas in unconstrained TKA 1.1% and in UKA 2.7% revision surgeries were identified. After 7 years the rates of aseptic revisions amounted to 3.3% for constrained TKA, 2.8% for unconstrained TKA and 7.8% for UKA. Ligament instability was the most common cause of aseptic revisions and accounted for 13.7% of unconstrained TKA. In constrained TKA ligament instability led to a revision in 2.8% of cases. In UKA, tibial loosening was identified to be the most common cause of revisions at 14.6%, whereas the progression of osteoarthritis was responsible for 7.9% of revisions. Ligament instability was observed in 14.1% of men compared with 15.9% of women in unconstrained TKA and in UKA in 4.6% of cases for both sexes.
In patients with UKA the rates of aseptic revision are significantly higher than in unconstrained and constrained TKA. Ligament instability was the most common cause of aseptic revision in unconstrained TKA. In UKA, tibial loosening was the most common cause of revision surgery, whereas the progression of osteoarthritis was the second most common cause. Comparable levels of ligament instability were observed in both sexes.
III, cohort study.
由于人口老龄化,全膝关节置换术(TKA)的植入率持续上升。初次TKA的无菌性翻修是翻修的主要原因之一。以下研究的目的是确定限制性和非限制性TKA以及单髁膝关节置换术(UKA)中无菌性翻修的发生率及原因。
借助德国关节置换登记处(EPRD)进行数据收集。据此确定无菌性翻修手术的原因。借助Kaplan-Meier估计分析无菌性翻修的发生率及比较情况。采用带有霍尔姆方法的多重卡方检验来确定侧副韧带缺陷的组间差异。
总共分析了300,998例膝关节置换病例,其中254,144例(84.4%)为非限制性TKA,9993例(3.3%)为限制性TKA,36,861例(12.3%)为UKA。与非限制性和限制性TKA相比,无菌性翻修率显著增加(p<0.0001)。在限制性TKA中,报告的无菌性翻修率为2.0%,而非限制性TKA为1.1%,UKA为2.7%。7年后,限制性TKA的无菌性翻修率为3.3%,非限制性TKA为2.8%,UKA为7.8%。韧带不稳定是无菌性翻修最常见的原因,占非限制性TKA的13.7%。在限制性TKA中,2.8%的病例因韧带不稳定导致翻修。在UKA中,胫骨松动是最常见的翻修原因,占14.6%,而骨关节炎进展导致的翻修占7.9%。在非限制性TKA中,14.1%的男性和15.9%的女性存在韧带不稳定,在UKA中,两性病例的韧带不稳定发生率均为4.6%。
UKA患者的无菌性翻修率显著高于非限制性和限制性TKA。韧带不稳定是非限制性TKA无菌性翻修最常见的原因。在UKA中,胫骨松动是翻修手术最常见的原因,而骨关节炎进展是第二常见的原因。两性的韧带不稳定水平相当。
III级,队列研究。