Hua Ming, Pan Ying, Jiang Changmei, Yu Peiyan, Li Xingang, Gao Yao, Xu Sijun, Pan Gangwei
National & Local Joint Engineering Research Center of Technical Fiber Composites for Safety and Protection, School of Textile and Clothing, Nantong University Nantong 226019 China
RSC Adv. 2024 Sep 23;14(41):30192-30200. doi: 10.1039/d4ra04919e. eCollection 2024 Sep 18.
Stereo-complexed polylactide (sc-PLA) nano-microspheres were separated by adding poor solvent to the poly(l-lactide) (PLLA)/poly(d-lactide) (PDLA) blend solution. The effects of different process parameters (concentration, processing method, ratio of PLLA/PDLA blend solution to poor solvent) on the microsphere particle size were investigated. The microscopic morphology, crystallinity, and thermal properties were investigated by Fourier transform infrared spectroscopy, differential scanning calorimetry, two-dimensional wide-angle X-ray diffraction, transmission electron microscopy and scanning electron microscopy. The results indicated that when the concentration reached 10 wt% and the PLLA/PDLA blend solution to poor solvent ratio was 1 : 5, the sc-PLA nano-microspheres exhibited more regular shape, good sphericity and uniform particle size, and the highest crystallinity. Additionally, the degree of crystallinity of the stereo-complexed crystals was as high as 39.60%, the rate of stereo-complexation was 99.65%, and the melting temperature reached 220 °C, indicating notable improvement in the crystallization and thermal properties. The sc-PLA nano-microspheres obtained in this research could be used as a nucleating agent for fibers and drug delivery carrier, and the sc-PLA nano-microspheres have broad application prospects in the textile and biomedical fields.
通过向聚（L-丙交酯）（PLLA）/聚（D-丙交酯）（PDLA）共混溶液中加入不良溶剂来分离立体复合聚丙交酯（sc-PLA）纳米微球。研究了不同工艺参数（浓度、加工方法、PLLA/PDLA共混溶液与不良溶剂的比例）对微球粒径的影响。通过傅里叶变换红外光谱、差示扫描量热法、二维广角X射线衍射、透射电子显微镜和扫描电子显微镜研究了微观形态、结晶度和热性能。结果表明，当浓度达到10 wt%且PLLA/PDLA共混溶液与不良溶剂的比例为1:5时，sc-PLA纳米微球呈现出更规则的形状、良好的球形度和均匀的粒径，且结晶度最高。此外，立体复合晶体的结晶度高达39.60%，立体复合率为99.65%，熔点达到220℃，表明结晶和热性能有显著改善。本研究制备的sc-PLA纳米微球可作为纤维的成核剂和药物递送载体，在纺织和生物医学领域具有广阔的应用前景。
