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超分子平台辅助的尿酸高灵敏度选择性识别 自组装探针的微环境调控

Supramolecular-platform-assisted selective recognition of uric acid with high sensitivity microenvironment modulation of a self-assembled probe.

机构信息

Department of Chemistry, University of Kalyani, Nadia, West Bengal-741235, India.

Department of Chemistry, Kazi Nazrul University, West Bengal-713340, Asansol, India.

出版信息

J Mater Chem B. 2024 Oct 2;12(38):9545-9549. doi: 10.1039/d4tb01502a.

DOI:10.1039/d4tb01502a
PMID:39315664
Abstract

This report demonstrates a unique route for translating a non-responsive fluorophore into a responsive one to optically recognize uric acid (UA) in physiological-mimicking conditions. The explicit 'turn ON-turn OFF' fluorescence switching upon sequential disaggregation-reaggregation of the self-aggregated 3,3'-bisindolyl(phenyl)methane molecules materializes a straightforward, trouble-free supramolecular UA sensing platform.

摘要

本报告展示了一种将非响应荧光团转化为响应荧光团的独特途径，用于在生理模拟条件下光学识别尿酸（UA）。通过自组装的 3,3'-双吲哚基（苯基）甲烷分子的顺序解聚-再组装实现明确的“开-关”荧光切换，为简单、无故障的超分子 UA 传感平台提供了可能。

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